Protein: TOR1
Serine/threonine-protein kinase TOR1 (EC 2.7.11.1) (Dominant rapamycin resistance protein 1) (Phosphatidylinositol kinase homolog TOR1) (Target of rapamycin kinase 1)

Gene: TOR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 147
UniProt ID: P35169

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0001558 - regulation of cell growth
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

715202

LST8
Target of rapamycin complex subunit LST8

7

15

Small-scale

0.965

High

589281

FKBP
FK506-binding protein 1

2

8

Small-scale

0.838

High

350865

YPT1
GTP-binding protein YPT1

2

3

Small-scale

0.806

High

715187

KOG1
Target of rapamycin complex 1 subunit KOG1

18

14

Small-scale

0.763

High

715247

TCO89
Target of rapamycin complex 1 subunit TCO89

6

1

Small-scale

0.733

High

515179

SCH9
Serine/threonine-protein kinase SCH9

6

20

Small-scale

0.729

High

696490

TOR2
Serine/threonine-protein kinase TOR2

2

17

Small-scale

0.712

High

577298

GLN3
Nitrogen regulatory protein GLN3

5

5

Small-scale

0.710

High

715230

2ABA
Protein phosphatase PP2A regulatory subunit B

1

3

High-throughput

0.691

High

715231

RAGAB
GTP-binding protein GTR1

3

7

Small-scale

0.661

High

715240

TAP42
Type 2A phosphatase-associated protein 42

3

1

Small-scale

0.656

High

715220

PIB2
Glutamine sensor PIB2

4

1

Small-scale

0.642

High

715205

RGD2
Rho-GTPase-activating protein RGD2

1

1

High-throughput

0.621

High

514549

BIK1
Nuclear fusion protein BIK1

2

3

Small-scale

0.620

High

613115

URE2
Transcriptional regulator URE2

2

1

Small-scale

0.619

High

715181

RTG3
Retrograde regulation protein 3

2

1

High-throughput

0.614

High

715197

SERA
D-3-phosphoglycerate dehydrogenase 1

2

1

Small-scale

0.594

High

448199

F16P
Fructose-1,6-bisphosphatase

2

2

Small-scale

0.584

High

715244

RTC1
Restriction of telomere capping protein 1

1

11

High-throughput

0.578

High

680600

HS104
Heat shock protein 104

2

6

High-throughput

0.576

High

690611

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

8

High-throughput

0.575

High

715174

TOR1
Serine/threonine-protein kinase TOR1

1

16

High-throughput

0.575

High

715179

SWD3
COMPASS component SWD3

1

10

High-throughput

0.575

High

705013

HSP78
Heat shock protein 78, mitochondrial

2

6

High-throughput

0.571

High

715228

APJ1
J domain-containing protein APJ1

2

8

High-throughput

0.571

High

715178

YPK3
Serine/threonine-protein kinase YPK3

1

20

Small-scale

0.561

High

604980

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.552

High

715235

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.547

High

605729

NPR1
Nitrogen permease reactivator protein

1

11

High-throughput

0.536

High

709292

MKS1
Negative regulator of RAS-cAMP pathway

1

1

High-throughput

0.536

High

715175

NNK1
Nitrogen network kinase 1

1

7

High-throughput

0.536

High

715176

KDX1
Serine/threonine-protein kinase KDX1

1

5

High-throughput

0.536

High

715184

KSP1
Serine/threonine-protein kinase KSP1

1

18

High-throughput

0.536

High

715201

SA185
SIT4-associating protein SAP185

1

5

High-throughput

0.536

High

715218

SAP4
SIT4-associating protein SAP4

1

5

High-throughput

0.536

High

715222

FMP48
Probable serine/threonine-protein kinase FMP48

1

8

High-throughput

0.536

High

715232

CDC14
Tyrosine-protein phosphatase CDC14

1

8

High-throughput

0.536

High

715236

SKY1
Serine/threonine-protein kinase SKY1

1

17

High-throughput

0.536

High

715196

VHR2
Transcription factor VHR2

1

1

Small-scale

0.527

High

715211

TRM61
tRNA

1

1

High-throughput

0.515

High

715252

PKH2
Serine/threonine-protein kinase PKH2

1

17

High-throughput

0.515

High

715214

TAX4
Protein TAX4

1

0

High-throughput

0.513

High

715253

YL108
BTB/POZ domain-containing protein YLR108C

1

0

High-throughput

0.513

High

599942

DAL81
Transcriptional activator protein DAL81

1

1

Small-scale

0.508

High

641126

DAL80
Nitrogen regulatory protein DAL80

1

5

Small-scale

0.508

High

715204

GZF3
Protein GZF3

1

5

Small-scale

0.508

High

715206

GAT1
Transcriptional regulatory protein GAT1

1

5

Small-scale

0.508

High

715250

BBP
Branchpoint-bridging protein

1

1

High-throughput

0.508

High

424844

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.501

High

520595

YPK1
Serine/threonine-protein kinase YPK1

1

20

Small-scale

0.501

High

622004

SSD1
Protein SSD1

1

3

High-throughput

0.501

High

713163

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

3

Small-scale

0.501

High

713283

WHI3
Protein WHI3

1

2

High-throughput

0.501

High

715199

VPS27
Vacuolar protein sorting-associated protein 27

1

5

Small-scale

0.501

High

715203

MAF1
Repressor of RNA polymerase III transcription MAF1

1

1

Small-scale

0.501

High

715209

SCD6
Protein SCD6

1

2

High-throughput

0.501

High

715249

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.493

High

600301

DAL82
Protein DAL82

1

0

Small-scale

0.486

High

554618

HSP26
Heat shock protein 26

1

2

High-throughput

0.481

High

570681

HXKG
Glucokinase-1

1

1

High-throughput

0.481

High

634474

MET14
Karyogamy protein KAR4

1

3

High-throughput

0.481

High

675723

RENT1
ATP-dependent helicase NAM7

1

8

High-throughput

0.481

High

691734

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

3

High-throughput

0.481

High

715207

WWM1
WW domain-containing protein WWM1

1

1

High-throughput

0.481

High

715213

LSM1
Sm-like protein LSm1

1

2

High-throughput

0.481

High

715216

PSP2
Protein PSP2

1

1

High-throughput

0.481

High

715223

RAGCD
GTP-binding protein GTR2

1

7

High-throughput

0.481

High

715225

DCP2
m7GpppN-mRNA hydrolase

1

3

High-throughput

0.481

High

715226

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.481

High

715239

ICY1
Interacting with cytoskeleton protein 1

1

1

High-throughput

0.481

High

715256

DCP1
mRNA-decapping enzyme subunit 1

1

1

High-throughput

0.481

High

524252

CAF20
Cap-associated protein CAF20

1

0

Small-scale

0.480

High

710846

LST4
Protein LST4

1

0

Small-scale

0.480

High

356387

H4
Histone H4

1

6

High-throughput

0.479

High

376718

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.479

High

543503

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.479

High

548527

GCN2
eIF-2-alpha kinase GCN2

1

10

Small-scale

0.479

High

604255

MDHC
Malate dehydrogenase, cytoplasmic

1

2

Small-scale

0.479

High

635830

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

High-throughput

0.479

High

661849

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

689746

SFP1
Transcription factor SFP1

1

3

Small-scale

0.479

High

713206

TSA1
Peroxiredoxin TSA1

1

1

Small-scale

0.479

High

715177

TTI1
TEL2-interacting protein 1

1

16

High-throughput

0.479

High

715182

NU170
Nucleoporin NUP170

1

2

High-throughput

0.479

High

715183

RCK1
Serine/threonine-protein kinase RCK1

1

16

High-throughput

0.479

High

715190

DHH1
ATP-dependent RNA helicase DHH1

1

4

High-throughput

0.479

High

715193

VAC8
Vacuolar protein 8

1

9

High-throughput

0.479

High

715229

H3
Histone H3

1

9

High-throughput

0.479

High

715238

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

715246

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.479

High

715254

LAS17
Proline-rich protein LAS17

1

7

Small-scale

0.479

High

715208

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

12

High-throughput

0.470

High

336673

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.460

High

400154

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.460

High

693389

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.460

High

715186

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.460

High

715192

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.460

High

715233

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.460

High

715237

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

0

High-throughput

0.460

High

715245

MCA1
Metacaspase-1

1

0

High-throughput

0.460

High

501284

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.458

High

657023

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

715200

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

715224

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.458

High

715248

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

715241

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.457

High

366083

HSP82
ATP-dependent molecular chaperone HSP82

1

13

High-throughput

0.445

High

450005

HSP73
Heat shock protein SSA3

1

12

High-throughput

0.445

High

490825

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

493619

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

510829

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

540556

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.445

High

627596

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.445

High

627903

SIS1
Protein SIS1

1

7

High-throughput

0.445

High

633113

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.445

High

650266

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.445

High

689860

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

694427

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

715185

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

715188

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.445

High

715189

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.445

High

715194

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.445

High

715198

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

715212

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

715215

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.445

High

715234

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

9

High-throughput

0.445

High

715243

BRE1
E3 ubiquitin-protein ligase BRE1

1

10

High-throughput

0.445

High

715251

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.445

High

715255

RUVB2
RuvB-like protein 2

1

19

High-throughput

0.445

High

452986

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.439

High

626428

ERG6
Sterol 24-C-methyltransferase ERG6

1

3

High-throughput

0.439

High

715242

PEX19
Peroxisomal membrane protein import receptor PEX19

1

1

High-throughput

0.439

High

701363

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

399224

FUR4
Uracil permease

1

0

High-throughput

0.426

High

715180

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

715191

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

715217

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

715227

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

541671

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

541946

MTF1
Mitochondrial transcription factor 1

1

0

High-throughput

0.269

Low

689778

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.251

Low

696963

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

715219

YGY5
Uncharacterized protein YGL235W

1

0

High-throughput

0.251

Low

715221

IMO32
Probable alcohol acetyltransferase

1

0

High-throughput

0.251

Low

715195

BIM1
Protein BIM1

1

0

Small-scale

0.249

Low

715210

STU2
Protein STU2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024