Protein: RL1
Large ribosomal subunit protein uL1 (50S ribosomal protein L1)

Gene: RL1, rplA
Organism: Escherichia coli K-12
Interactions: 165
UniProt ID: P0A7L0

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000049 - tRNA binding
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

460735

RHLB
ATP-dependent RNA helicase RhlB

2

4

High-throughput

0.759

High

460798

SRMB
ATP-dependent RNA helicase SrmB

2

5

High-throughput

0.759

High

460808

RECG
ATP-dependent DNA helicase RecG

1

1

High-throughput

0.691

High

460809

RHLE
ATP-dependent RNA helicase RhlE

1

2

High-throughput

0.691

High

460742

CSPE
Cold shock-like protein CspE

3

15

High-throughput

0.662

High

460750

CSPC
Cold shock-like protein CspC

3

15

High-throughput

0.657

High

460843

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

3

1

High-throughput

0.657

High

460743

CSPG
Cold shock-like protein CspG

2

15

High-throughput

0.628

High

460747

DEAD
ATP-dependent RNA helicase DeaD

1

2

High-throughput

0.625

High

460754

YBCJ
Putative RNA-binding protein YbcJ

3

0

High-throughput

0.616

High

460749

CSPA
Cold shock protein CspA

2

15

High-throughput

0.612

High

460752

RLUC
Ribosomal large subunit pseudouridine synthase C

2

3

High-throughput

0.612

High

460736

SYT
Threonine--tRNA ligase

2

1

High-throughput

0.611

High

460801

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

2

2

High-throughput

0.611

High

460799

RNE
Ribonuclease E

3

0

Small-scale

0.607

High

368597

DPO3E
DNA polymerase III subunit epsilon

2

2

High-throughput

0.601

High

460854

SUFC
Probable ATP-dependent transporter SufC

1

0

High-throughput

0.593

High

340850

RPOD
RNA polymerase sigma factor RpoD

2

1

High-throughput

0.588

High

393720

PNP
Polyribonucleotide nucleotidyltransferase

2

3

High-throughput

0.588

High

460748

ULAR
HTH-type transcriptional regulator UlaR

2

1

High-throughput

0.588

High

460787

SRP54
Signal recognition particle protein

2

2

High-throughput

0.588

High

460790

RLME
Ribosomal RNA large subunit methyltransferase E

2

3

High-throughput

0.588

High

460793

SELB
Selenocysteine-specific elongation factor

2

3

High-throughput

0.588

High

460795

ICLR
Transcriptional repressor IclR

2

1

High-throughput

0.588

High

460797

RNR
Ribonuclease R

2

2

High-throughput

0.588

High

460816

AIDB
Putative acyl-CoA dehydrogenase AidB

2

2

High-throughput

0.588

High

460818

CBPA
Curved DNA-binding protein

2

2

High-throughput

0.588

High

460836

RL4
Large ribosomal subunit protein uL4

2

2

High-throughput

0.588

High

460760

DNAB
Replicative DNA helicase

2

0

High-throughput

0.585

High

460820

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.585

High

460844

RLMI
Ribosomal RNA large subunit methyltransferase I

2

1

High-throughput

0.584

High

460824

DPPF
Dipeptide transport ATP-binding protein DppF

1

0

High-throughput

0.578

High

460734

UVRC
UvrABC system protein C

2

0

High-throughput

0.576

High

460772

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

460791

DPO3A
DNA polymerase III subunit alpha

2

0

High-throughput

0.576

High

460852

DCYD
D-cysteine desulfhydrase

2

0

High-throughput

0.576

High

336958

PHSM
Maltodextrin phosphorylase

2

0

High-throughput

0.563

High

458673

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

2

0

High-throughput

0.563

High

459573

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

2

0

High-throughput

0.563

High

460265

PYRH
Uridylate kinase

2

0

High-throughput

0.563

High

460769

YIBL
Uncharacterized protein YibL

2

0

High-throughput

0.563

High

460832

HRPA
ATP-dependent RNA helicase HrpA

1

2

High-throughput

0.553

High

460775

DCM
DNA-cytosine methyltransferase

2

1

High-throughput

0.549

High

460810

HOLB
DNA polymerase III subunit delta'

2

1

High-throughput

0.537

High

357013

RS7
Small ribosomal subunit protein uS7

1

2

High-throughput

0.536

High

460464

RL11
Large ribosomal subunit protein uL11

1

2

High-throughput

0.536

High

460724

RS12
Small ribosomal subunit protein uS12

1

1

High-throughput

0.536

High

460726

RS19
Small ribosomal subunit protein uS19

1

2

High-throughput

0.536

High

460728

RS5
Small ribosomal subunit protein uS5

1

2

High-throughput

0.536

High

460744

CSPI
Cold shock-like protein CspI

1

15

High-throughput

0.536

High

460762

DBHB
DNA-binding protein HU-beta

1

2

High-throughput

0.536

High

460771

RL16
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

460780

PARC
DNA topoisomerase 4 subunit A

1

1

High-throughput

0.536

High

460784

RL17
Large ribosomal subunit protein bL17

1

2

High-throughput

0.536

High

460786

RS1
Small ribosomal subunit protein bS1

1

6

High-throughput

0.536

High

460789

TRML
tRNA

1

3

High-throughput

0.536

High

460821

CSPB
Cold shock-like protein CspB

1

15

High-throughput

0.536

High

460831

ARFB
Peptidyl-tRNA hydrolase ArfB

1

2

High-throughput

0.536

High

460819

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.517

High

381649

3MG2
DNA-3-methyladenine glycosylase 2

1

0

High-throughput

0.513

High

460725

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.513

High

460727

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

460731

SSRP
SsrA-binding protein

1

0

High-throughput

0.513

High

460738

MATP
Macrodomain Ter protein

1

0

High-throughput

0.513

High

460751

GLNB
Nitrogen regulatory protein P-II 1

1

0

High-throughput

0.513

High

460753

YBAK
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK

1

0

High-throughput

0.513

High

460755

COABC
Coenzyme A biosynthesis bifunctional protein CoaBC

1

0

High-throughput

0.513

High

460756

DNAG
DNA primase

1

0

High-throughput

0.513

High

460761

GLMU
Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase

1

0

High-throughput

0.513

High

460763

HSLR
Heat shock protein 15

1

0

High-throughput

0.513

High

460773

RS15
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

460785

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.513

High

460803

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

1

0

High-throughput

0.513

High

460805

HEMH
Ferrochelatase

1

0

High-throughput

0.513

High

460806

FMT
Methionyl-tRNA formyltransferase

1

0

High-throughput

0.513

High

460826

WAAF
Lipopolysaccharide heptosyltransferase 2

1

0

High-throughput

0.513

High

460835

TILS
tRNA(Ile)-lysidine synthase

1

0

High-throughput

0.513

High

460857

THII
tRNA sulfurtransferase

1

0

High-throughput

0.513

High

460859

MAA
Maltose O-acetyltransferase

1

0

High-throughput

0.513

High

460723

RL9
Large ribosomal subunit protein bL9

1

1

Small-scale

0.501

High

460812

PQQL
Probable zinc protease PqqL

1

2

High-throughput

0.500

High

439008

YCIH
Uncharacterized protein YciH

1

1

High-throughput

0.489

High

460800

PDEL
Cyclic di-GMP phosphodiesterase PdeL

1

1

High-throughput

0.489

High

460813

RLUF
Dual-specificity RNA pseudouridine synthase RluF

1

1

High-throughput

0.489

High

442660

DNAJ
Chaperone protein DnaJ

1

2

High-throughput

0.484

High

458520

HSCB
Co-chaperone protein HscB

1

1

High-throughput

0.484

High

458966

IHFA
Integration host factor subunit alpha

1

2

High-throughput

0.484

High

458996

IHFB
Integration host factor subunit beta

1

2

High-throughput

0.484

High

460730

RPOA
DNA-directed RNA polymerase subunit alpha

1

1

High-throughput

0.484

High

460741

CSPD
Cold shock-like protein CspD

1

15

High-throughput

0.484

High

460764

ALLR
HTH-type transcriptional repressor AllR

1

1

High-throughput

0.484

High

460788

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

3

High-throughput

0.484

High

460792

RPOS
RNA polymerase sigma factor RpoS

1

1

High-throughput

0.484

High

460828

RLUB
Ribosomal large subunit pseudouridine synthase B

1

3

High-throughput

0.484

High

460807

MAK
Fructokinase

1

0

High-throughput

0.479

High

460834

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.479

High

460838

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.479

High

460796

PARE
DNA topoisomerase 4 subunit B

1

1

High-throughput

0.479

High

458285

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

458708

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

458899

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

459961

RPPH
RNA pyrophosphohydrolase

1

0

High-throughput

0.464

High

460729

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.464

High

460732

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.464

High

460745

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

460757

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

460778

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.464

High

404169

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

0

High-throughput

0.458

High

452013

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

0

High-throughput

0.458

High

460223

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.458

High

460737

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.458

High

460739

YJGA
UPF0307 protein YjgA

1

0

High-throughput

0.458

High

460740

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.458

High

460746

LON
Lon protease

1

0

High-throughput

0.458

High

460758

KDSC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC

1

0

High-throughput

0.458

High

460768

KPYK1
Pyruvate kinase I

1

0

High-throughput

0.458

High

460777

NSRR
HTH-type transcriptional repressor NsrR

1

0

High-throughput

0.458

High

460782

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

0

High-throughput

0.458

High

460783

SPOT
Bifunctional

1

0

High-throughput

0.458

High

460802

ISPA
Farnesyl diphosphate synthase

1

0

High-throughput

0.458

High

460817

TKT2
Transketolase 2

1

0

High-throughput

0.458

High

460837

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.458

High

460839

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

460858

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.458

High

460815

PDEC
Probable cyclic di-GMP phosphodiesterase PdeC

1

1

High-throughput

0.457

High

460794

SRLR
Glucitol operon repressor

1

1

High-throughput

0.442

High

460860

UACF
Putative oxidoreductase UacF

1

2

High-throughput

0.437

High

460733

TIG
Trigger factor

1

0

Small-scale

0.426

High

460861

YAJL
Protein/nucleic acid deglycase 3

1

0

Small-scale

0.426

High

460851

YEAO
Uncharacterized protein YeaO

2

0

High-throughput

0.318

High

460781

ATL
DNA base-flipping protein

2

0

High-throughput

0.307

High

460842

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

460846

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

2

0

High-throughput

0.307

High

416834

DPO3X
DNA polymerase III subunit tau

1

0

High-throughput

0.279

Low

421194

PRIB
Primosomal replication protein N

1

0

High-throughput

0.279

Low

459827

MOAC
Cyclic pyranopterin monophosphate synthase

1

0

High-throughput

0.279

Low

460765

RUTR
HTH-type transcriptional regulator RutR

1

0

High-throughput

0.279

Low

460767

YDIE
Uncharacterized protein YdiE

1

0

High-throughput

0.279

Low

460776

DMA
DNA adenine methylase

1

0

High-throughput

0.279

Low

460804

PRIC
Primosomal replication protein N''

1

0

High-throughput

0.279

Low

460811

RIBX
N-glycosidase YbiA

1

0

High-throughput

0.279

Low

460822

YCHJ
UPF0225 protein YchJ

1

0

High-throughput

0.279

Low

460833

YHBQ
UPF0213 protein YhbQ

1

0

High-throughput

0.279

Low

460840

WCAK
Colanic acid biosynthesis protein WcaK

1

0

High-throughput

0.279

Low

460841

RLMC
23S rRNA

1

0

High-throughput

0.279

Low

460845

YMGA
Probable two-component-system connector protein YmgA

1

0

High-throughput

0.279

Low

460848

YNEG
Uncharacterized protein YneG

1

0

High-throughput

0.279

Low

460850

NIMR
HTH-type transcriptional regulator NimR

1

0

High-throughput

0.279

Low

460853

YGAV
Probable HTH-type transcriptional regulator YgaV

1

0

High-throughput

0.279

Low

460855

YDHQ
Protein YdhQ

1

0

High-throughput

0.279

Low

460766

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

460770

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

460759

KDTA
3-deoxy-D-manno-octulosonic acid transferase

1

0

High-throughput

0.253

Low

460823

DCTR
HTH-type transcriptional regulator DctR

1

0

High-throughput

0.253

Low

367356

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

460774

PAEA
Polyamine export protein

1

0

High-throughput

0.249

Low

460779

OPPB
Oligopeptide transport system permease protein OppB

1

0

High-throughput

0.249

Low

460814

YJBH
Uncharacterized lipoprotein YjbH

1

0

High-throughput

0.249

Low

460825

YHJG
AsmA family protein YhjG

1

0

High-throughput

0.249

Low

460827

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

460829

YJIE
HTH-type transcriptional regulator YjiE

1

0

High-throughput

0.249

Low

460830

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low

460847

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

460849

YNHG
Probable L,D-transpeptidase YnhG

1

0

High-throughput

0.249

Low

460856

YBAY
Uncharacterized lipoprotein YbaY

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024