Protein: DLDH
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Glycine cleavage system L protein)

Gene: DLDH, lpdA
Organism: Escherichia coli K-12
Interactions: 93
UniProt ID: P0A9P0

Gene Ontology (top 5):
GO:0004148 - dihydrolipoyl dehydrogenase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005960 - glycine cleavage complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420918

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

3

12

High-throughput

0.864

High

465061

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

2

12

High-throughput

0.803

High

465041

DLDH
Dihydrolipoyl dehydrogenase

2

11

Small-scale

0.754

High

465065

THIO2
Thioredoxin 2

1

6

High-throughput

0.691

High

465073

TRHO
tRNA uridine(34) hydroxylase

1

0

High-throughput

0.578

High

340914

DPO1
DNA polymerase I

1

1

High-throughput

0.536

High

368641

UVRD
DNA helicase II

1

2

High-throughput

0.536

High

415753

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

439448

RECB
RecBCD enzyme subunit RecB

1

2

High-throughput

0.536

High

445979

T1RK
Type I restriction enzyme EcoKI endonuclease subunit

1

1

High-throughput

0.536

High

446942

EX3
Exodeoxyribonuclease III

1

1

High-throughput

0.536

High

457382

ISCS
Cysteine desulfurase IscS

1

1

High-throughput

0.536

High

463373

UVRB
UvrABC system protein B

1

1

High-throughput

0.536

High

465070

RECQ
ATP-dependent DNA helicase RecQ

1

1

High-throughput

0.536

High

465074

MNME
tRNA modification GTPase MnmE

1

1

High-throughput

0.536

High

465076

RAVA
ATPase RavA

1

2

High-throughput

0.536

High

465080

YEJF
Uncharacterized ABC transporter ATP-binding protein YejF

1

1

High-throughput

0.536

High

465099

FADI
3-ketoacyl-CoA thiolase FadI

1

1

High-throughput

0.536

High

465102

FADJ
Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase

1

1

High-throughput

0.536

High

336964

PHSM
Maltodextrin phosphorylase

1

0

High-throughput

0.513

High

368567

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.513

High

436656

ILVB
Acetolactate synthase isozyme 1 large subunit

1

0

High-throughput

0.513

High

460394

RIBB
3,4-dihydroxy-2-butanone 4-phosphate synthase

1

0

High-throughput

0.513

High

463397

UVRC
UvrABC system protein C

1

0

High-throughput

0.513

High

465044

RLUC
Ribosomal large subunit pseudouridine synthase C

1

0

High-throughput

0.513

High

465045

YBAK
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK

1

0

High-throughput

0.513

High

465051

CHEY
Chemotaxis protein CheY

1

0

High-throughput

0.513

High

465062

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

465068

DPO3A
DNA polymerase III subunit alpha

1

0

High-throughput

0.513

High

465072

YICC
Endoribonuclease YicC

1

0

High-throughput

0.513

High

465078

FDHD
Sulfur carrier protein FdhD

1

0

High-throughput

0.513

High

465079

DUSC
tRNA-dihydrouridine(16) synthase

1

0

High-throughput

0.513

High

465082

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.513

High

465083

CSPB
Cold shock-like protein CspB

1

0

High-throughput

0.513

High

465090

END8
Endonuclease 8

1

0

High-throughput

0.513

High

465093

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.513

High

465096

BLUF
Blue light- and temperature-regulated antirepressor BluF

1

0

High-throughput

0.513

High

465100

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

1

0

High-throughput

0.513

High

465101

DGCM
Diguanylate cyclase DgcM

1

0

High-throughput

0.513

High

465075

GLUQ
Glutamyl-Q tRNA(Asp) synthetase

1

2

High-throughput

0.500

High

465069

TOP3
DNA topoisomerase 3

1

1

High-throughput

0.489

High

465084

HRPB
ATP-dependent RNA helicase HrpB

1

1

High-throughput

0.489

High

465086

IDND
L-idonate 5-dehydrogenase

1

1

High-throughput

0.489

High

465103

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

1

High-throughput

0.489

High

457337

ACP
Acyl carrier protein

1

1

High-throughput

0.484

High

465042

ULAR
HTH-type transcriptional regulator UlaR

1

1

High-throughput

0.484

High

465043

ZNUC
Zinc import ATP-binding protein ZnuC

1

1

High-throughput

0.484

High

465055

GYRA
DNA gyrase subunit A

1

1

High-throughput

0.484

High

465060

ODO1
2-oxoglutarate dehydrogenase E1 component

1

7

High-throughput

0.484

High

465064

PARC
DNA topoisomerase 4 subunit A

1

1

High-throughput

0.484

High

465066

IBPA
Small heat shock protein IbpA

1

1

High-throughput

0.484

High

465067

IBPB
Small heat shock protein IbpB

1

1

High-throughput

0.484

High

457578

CH60
Chaperonin GroEL

1

1

Small-scale

0.479

High

457427

END4
Endonuclease 4

1

0

High-throughput

0.464

High

458821

RSMG
Ribosomal RNA small subunit methyltransferase G

1

0

High-throughput

0.464

High

460081

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.464

High

460141

PPK1
Polyphosphate kinase

1

0

High-throughput

0.464

High

462588

RNH
Ribonuclease HI

1

0

High-throughput

0.464

High

463168

UBIE
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE

1

0

High-throughput

0.464

High

464674

LDCI
Inducible lysine decarboxylase

1

0

High-throughput

0.464

High

464762

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

465046

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.464

High

465052

UVRY
Response regulator UvrY

1

0

High-throughput

0.464

High

465054

FUCM
L-fucose mutarotase

1

0

High-throughput

0.464

High

465057

NARJ
Nitrate reductase molybdenum cofactor assembly chaperone NarJ

1

0

High-throughput

0.464

High

465058

RRAB
Regulator of ribonuclease activity B

1

0

High-throughput

0.464

High

465063

OGT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.464

High

465092

NFI
Endonuclease V

1

0

High-throughput

0.464

High

392880

RECD
RecBCD enzyme subunit RecD

1

0

High-throughput

0.279

Low

465049

PDHR
Pyruvate dehydrogenase complex repressor

1

0

High-throughput

0.279

Low

465059

NUDB
Dihydroneopterin triphosphate diphosphatase

1

0

High-throughput

0.279

Low

465071

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

0

High-throughput

0.279

Low

465077

NNR
Bifunctional NAD(P)H-hydrate repair enzyme Nnr

1

0

High-throughput

0.279

Low

465081

NAPA
Periplasmic nitrate reductase

1

0

High-throughput

0.279

Low

465085

INTS
Prophage integrase IntS

1

0

High-throughput

0.279

Low

465087

HRPA
ATP-dependent RNA helicase HrpA

1

0

High-throughput

0.279

Low

465088

YRAN
UPF0102 protein YraN

1

0

High-throughput

0.279

Low

465089

UBIU
Ubiquinone biosynthesis protein UbiU

1

0

High-throughput

0.279

Low

465091

YGFF
Uncharacterized oxidoreductase YgfF

1

0

High-throughput

0.279

Low

465094

YBJX
Uncharacterized protein YbjX

1

0

High-throughput

0.279

Low

465095

BLUR
HTH-type transcriptional repressor BluR

1

0

High-throughput

0.279

Low

465097

PAAX
Transcriptional repressor PaaX

1

0

High-throughput

0.279

Low

465098

YNFB
UPF0482 protein YnfB

1

0

High-throughput

0.279

Low

465104

UACR
Putative uric acid sigma-54-dependent transcriptional regulator UacR

1

0

High-throughput

0.279

Low

404422

T1SK
Type I restriction enzyme EcoKI specificity subunit

1

0

High-throughput

0.261

Low

462604

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

463478

TRMB
tRNA

1

0

High-throughput

0.253

Low

465047

END3
Endonuclease III

1

0

High-throughput

0.253

Low

465048

SURA
Chaperone SurA

1

0

High-throughput

0.253

Low

465050

PINR
Serine recombinase PinR

1

0

High-throughput

0.253

Low

465053

DMA
DNA adenine methylase

1

0

High-throughput

0.253

Low

465056

HYCI
Hydrogenase 3 maturation protease

1

0

High-throughput

0.253

Low


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Last updated: 15 Jul 2024