Protein: DOK6
Docking protein 6 (Downstream of tyrosine kinase 6)

Gene: DOK6
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q6PKX4

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0043410 - positive regulation of MAPK cascade

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1059997

LASP1
LIM and SH3 domain protein 1

2

2

High-throughput

0.783

High

1081513

NTRK3
NT-3 growth factor receptor

1

20

Small-scale

0.766

High

1162743

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.742

High

338574

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

383858

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

434219

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.618

High

1162741

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.573

High

993472

TLE5
TLE family member 5

2

1

High-throughput

0.553

High

1162734

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

1

High-throughput

0.553

High

1162739

PPL13
Placental protein 13-like

2

1

High-throughput

0.553

High

1162735

CUL9
Cullin-9

1

1

High-throughput

0.479

High

1162744

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

898037

YPEL3
Protein yippee-like 3

1

2

High-throughput

0.439

High

1162740

ESR2
Estrogen receptor beta

1

4

High-throughput

0.407

High

645982

CRBB3
Beta-crystallin B3

2

0

High-throughput

0.316

High

978196

ARI5A
AT-rich interactive domain-containing protein 5A

2

0

High-throughput

0.316

High

1157247

ZNT6
Zinc transporter 6

2

0

High-throughput

0.316

High

1162737

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High

1162738

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

2

0

High-throughput

0.316

High

1162742

TBX15
T-box transcription factor TBX15

2

0

High-throughput

0.316

High

1162745

F86C1
Putative protein FAM86C1P

2

0

High-throughput

0.316

High

1158724

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

851167

CNN1
Calponin-1

1

0

High-throughput

0.269

Low

1162736

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024