Protein: CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4 (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector)

Gene: CCR4
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P31384

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680029

POP2
Poly(A) ribonuclease POP2

21

14

Small-scale

0.769

High

636113

NOT1
General negative regulator of transcription subunit 1

16

8

Small-scale

0.764

High

680052

CAF40
Protein CAF40

11

5

Small-scale

0.759

High

680021

NOT4
General negative regulator of transcription subunit 4

12

3

Small-scale

0.757

High

409826

NOT2
General negative regulator of transcription subunit 2

6

10

Small-scale

0.730

High

680071

NOT5
General negative regulator of transcription subunit 5

5

6

Small-scale

0.721

High

680050

CF130
Protein CAF130

6

0

Small-scale

0.706

High

605497

DBF2
Cell cycle protein kinase DBF2

3

3

Small-scale

0.685

High

680012

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

19

High-throughput

0.665

High

409961

NOT3
General negative regulator of transcription subunit 3

3

6

Small-scale

0.658

High

680037

NACB2
Nascent polypeptide-associated complex subunit beta-2

3

3

Small-scale

0.650

High

680056

ACT
Actin

1

6

High-throughput

0.646

High

680057

PRS8
26S proteasome regulatory subunit 8 homolog

2

1

Small-scale

0.621

High

680064

PUF3
mRNA-binding protein PUF3

2

4

Small-scale

0.611

High

680046

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

1

Small-scale

0.586

High

376680

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

8

Small-scale

0.585

High

555878

VATB
V-type proton ATPase subunit B

2

3

High-throughput

0.584

High

633018

MAS5
Mitochondrial protein import protein MAS5

2

6

High-throughput

0.584

High

680030

MPT5
Suppressor protein MPT5

2

4

Small-scale

0.584

High

680070

HSP42
Heat shock protein 42

2

2

High-throughput

0.584

High

490585

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.571

High

627786

SIS1
Protein SIS1

2

3

High-throughput

0.571

High

680017

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

510547

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

680035

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

680020

GCN1
eIF-2-alpha kinase activator GCN1

2

1

High-throughput

0.549

High

680065

SGT1
Protein SGT1

1

11

High-throughput

0.541

High

549713

STI1
Heat shock protein STI1

1

9

High-throughput

0.536

High

680016

PP12
Serine/threonine-protein phosphatase PP1-2

1

12

High-throughput

0.536

High

680051

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

680061

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.536

High

680055

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.518

High

680031

SSN3
Meiotic mRNA stability protein kinase SSN3

1

2

Small-scale

0.515

High

587296

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.513

High

630393

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.513

High

680014

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.513

High

680049

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.513

High

680024

CAF4
CCR4-associated factor 4

1

8

Small-scale

0.508

High

680058

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

3

Small-scale

0.508

High

477169

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

549795

UBC4
Ubiquitin-conjugating enzyme E2 4

1

3

Small-scale

0.501

High

360786

TBB
Tubulin beta chain

1

1

High-throughput

0.500

High

424391

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

498461

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

554587

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

628930

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.500

High

680067

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.489

High

680034

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.486

High

680043

CAF16
CCR4-associated factor 16

1

0

Small-scale

0.486

High

516282

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.480

High

381434

GAL1
Galactokinase

1

0

High-throughput

0.479

High

454227

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.479

High

375311

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.479

High

501333

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

Small-scale

0.479

High

557934

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

619125

SPT6
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

629414

PUF4
Pumilio homology domain family member 4

1

4

Small-scale

0.479

High

661568

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

680018

PRS6A
26S proteasome regulatory subunit 6A

1

1

Small-scale

0.479

High

680023

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.479

High

680025

GBLP
Small ribosomal subunit protein RACK1

1

7

Small-scale

0.479

High

680026

HMT1
Protein arginine N-methyltransferase 1

1

5

Small-scale

0.479

High

680038

TM108
Protein TMA108

1

5

High-throughput

0.479

High

680054

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

680066

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

680072

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

6

Small-scale

0.479

High

680044

MDV1
Mitochondrial division protein 1

1

8

High-throughput

0.464

High

515105

TAF13
Transcription initiation factor TFIID subunit 13

1

0

Small-scale

0.460

High

524209

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

568857

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

644975

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

680013

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

680027

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

680040

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

680042

T2FB
Transcription initiation factor IIF subunit beta

1

0

Small-scale

0.458

High

680048

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.458

High

680053

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

0

Small-scale

0.458

High

680060

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

680062

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

680063

CDC73
Cell division control protein 73

1

0

Small-scale

0.458

High

680068

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

680069

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

341957

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

423793

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.457

High

520800

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.457

High

587981

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.457

High

365944

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

399365

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

493411

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

498838

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

680015

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

680019

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

680022

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.445

High

680036

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.445

High

680041

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

407788

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.426

High

680032

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

680047

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

680039

DJP1
DnaJ-like protein 1

1

5

High-throughput

0.407

High

680033

TCPZ
T-complex protein 1 subunit zeta

2

0

High-throughput

0.313

High

680028

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.299

High

680059

YM46
Uncharacterized protein YMR181C

1

0

High-throughput

0.265

Low

378306

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

680045

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024