Protein: PRP46
Pre-mRNA-splicing factor PRP46 (Complexed with CEF1 protein 1) (PRP nineteen-associated complex protein 50) (PRP19-associated complex protein 50) (Pre-mRNA-processing protein 46)

Gene: PRP46
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: Q12417

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005681 - spliceosomal complex
GO:0005737 - cytoplasm
GO:0071011 - precatalytic spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

655772

PRP45
Pre-mRNA-processing protein 45

9

5

Small-scale

0.874

High

629406

BUD31
Pre-mRNA-splicing factor BUD31

2

2

High-throughput

0.789

High

704739

PRP8
Pre-mRNA-splicing factor 8

2

6

High-throughput

0.789

High

731790

SN114
Pre-mRNA-splicing factor SNU114

2

9

High-throughput

0.789

High

977090

CEF1
Pre-mRNA-splicing factor CEF1

7

16

Small-scale

0.747

High

692380

PRP19
Pre-mRNA-processing factor 19

7

18

Small-scale

0.744

High

1014929

CWC2
Pre-mRNA-splicing factor CWC2

5

3

Small-scale

0.718

High

1015445

CLF1
Pre-mRNA-splicing factor CLF1

5

20

Small-scale

0.713

High

746889

SLT11
Pre-mRNA-splicing factor SLT11

4

2

High-throughput

0.697

High

997048

RU2A
U2 small nuclear ribonucleoprotein A'

4

14

Small-scale

0.686

High

859466

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

13

High-throughput

0.671

High

697280

BRR2
Pre-mRNA-splicing helicase BRR2

3

20

High-throughput

0.667

High

971707

CUS1
Cold sensitive U2 snRNA suppressor 1

3

2

High-throughput

0.662

High

766979

RSMB
Small nuclear ribonucleoprotein-associated protein B

3

4

High-throughput

0.656

High

657780

YJU2
Splicing factor YJU2

5

2

Small-scale

0.650

High

770350

RUXG
Small nuclear ribonucleoprotein G

3

5

High-throughput

0.643

High

873682

RUXF
Small nuclear ribonucleoprotein F

3

3

High-throughput

0.643

High

996594

NCBP2
Nuclear cap-binding protein subunit 2

3

8

High-throughput

0.640

High

513275

SSB1
Ribosome-associated molecular chaperone SSB1

3

19

High-throughput

0.633

High

976136

CWC21
Pre-mRNA-splicing factor CWC21

3

0

Small-scale

0.622

High

778646

PRP17
Pre-mRNA-processing factor 17

1

18

High-throughput

0.618

High

980241

RSE1
Pre-mRNA-splicing factor RSE1

1

14

High-throughput

0.618

High

1015581

PRP46
Pre-mRNA-splicing factor PRP46

1

16

High-throughput

0.618

High

598658

ISY1
Pre-mRNA-splicing factor ISY1

2

2

High-throughput

0.611

High

861588

CWC22
Pre-mRNA-splicing factor CWC22

2

2

High-throughput

0.611

High

978489

SYF1
Pre-mRNA-splicing factor SYF1

2

19

High-throughput

0.611

High

986612

SMD2
Small nuclear ribonucleoprotein Sm D2

2

2

High-throughput

0.611

High

699220

PEP12
Syntaxin PEP12

3

1

Small-scale

0.603

High

987208

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.602

High

991159

PRP11
Pre-mRNA-splicing factor PRP11

2

3

High-throughput

0.601

High

410198

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

2

High-throughput

0.595

High

622354

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

16

Small-scale

0.595

High

556388

VATB
V-type proton ATPase subunit B

2

8

High-throughput

0.588

High

977582

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.586

High

748098

NTC20
Pre-mRNA-splicing factor NTC20

2

0

High-throughput

0.585

High

861085

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.585

High

985866

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.585

High

589467

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

16

High-throughput

0.584

High

710241

NCBP1
Nuclear cap-binding protein complex subunit 1

2

2

High-throughput

0.584

High

690718

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

2

4

High-throughput

0.567

High

495354

HSP72
Heat shock protein SSA2

2

19

High-throughput

0.552

High

865380

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

562306

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

5

High-throughput

0.536

High

676487

XPO1
Exportin-1

1

12

High-throughput

0.536

High

775732

MSL1
U2 small nuclear ribonucleoprotein B''

1

19

High-throughput

0.536

High

856948

CWC23
Pre-mRNA-splicing factor CWC23

1

13

High-throughput

0.536

High

748203

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.513

High

987744

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

560834

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.500

High

811505

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.500

High

761112

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

772946

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.489

High

623517

KPC1
Protein kinase C-like 1

1

12

Small-scale

0.481

High

554258

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

18

High-throughput

0.479

High

586543

PRP9
Pre-mRNA-splicing factor PRP9

1

2

High-throughput

0.479

High

692442

PRP21
Pre-mRNA-splicing factor PRP21

1

2

High-throughput

0.479

High

775708

IST3
U2 snRNP component IST3

1

11

High-throughput

0.479

High

795437

SMD3
Small nuclear ribonucleoprotein Sm D3

1

15

High-throughput

0.479

High

809558

CWC26
Pre-mRNA-splicing factor CWC26

1

2

High-throughput

0.479

High

836952

SF3B1
U2 snRNP component HSH155

1

15

High-throughput

0.479

High

970254

SMD1
Small nuclear ribonucleoprotein Sm D1

1

3

High-throughput

0.479

High

972435

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.479

High

992642

PML1
Pre-mRNA leakage protein 1

1

2

High-throughput

0.479

High

1015582

HSH49
Protein HSH49

1

6

High-throughput

0.479

High

733105

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

733488

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.458

High

989436

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

342147

ATPB
ATP synthase subunit beta, mitochondrial

1

8

High-throughput

0.457

High

378414

LEU3
3-isopropylmalate dehydrogenase

1

8

High-throughput

0.457

High

588271

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.457

High

424772

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.445

High

492897

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.445

High

695848

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

769849

SSB2
Ribosome-associated molecular chaperone SSB2

1

19

High-throughput

0.445

High

851997

HFM1
ATP-dependent DNA helicase MER3

1

16

Small-scale

0.439

High

987237

TDA5
Uncharacterized oxidoreductase TDA5

1

1

Small-scale

0.439

High

1015198

YRA1
RNA annealing protein YRA1

1

9

High-throughput

0.437

High

810208

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

772595

JEM1
DnaJ-like chaperone JEM1

1

8

High-throughput

0.407

High

441689

MSS18
Protein MSS18

1

0

High-throughput

0.269

Low

744011

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

0

Small-scale

0.251

Low

966053

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.249

Low

978389

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024