Protein: RPB1
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)

Gene: RPB1, Polr2a
Organism: Mus musculus
Interactions: 42
UniProt ID: P08775

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0001046 - core promoter sequence-specific DNA binding
GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444976

DIDO1
Death-inducer obliterator 1

1

4

Small-scale

0.618

High

444968

SRSF2
Serine/arginine-rich splicing factor 2

2

0

Small-scale

0.585

High

444985

CDK9
Cyclin-dependent kinase 9

2

12

Small-scale

0.584

High

444988

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

Small-scale

0.578

High

444965

ERR2
Steroid hormone receptor ERR2

1

5

High-throughput

0.554

High

444969

GPBP1
Vasculin

1

0

Small-scale

0.537

High

444970

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.536

High

444974

NSD2
Histone-lysine N-methyltransferase NSD2

1

11

Small-scale

0.536

High

444971

SRSF1
Serine/arginine-rich splicing factor 1

1

3

Small-scale

0.515

High

444973

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.513

High

444991

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

Small-scale

0.500

High

444953

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

Small-scale

0.479

High

444956

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

Small-scale

0.479

High

444960

NF1
Neurofibromin

1

1

Small-scale

0.479

High

444961

SMCA4
Transcription activator BRG1

1

9

Small-scale

0.479

High

444962

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

444964

LEO1
RNA polymerase-associated protein LEO1

1

2

Small-scale

0.479

High

444966

DDX5
Probable ATP-dependent RNA helicase DDX5

1

3

Small-scale

0.479

High

444975

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

444979

SMYD2
N-lysine methyltransferase SMYD2

1

2

Small-scale

0.479

High

444980

ELF5
ETS-related transcription factor Elf-5

1

1

High-throughput

0.479

High

444981

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

Small-scale

0.479

High

444984

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

444987

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.479

High

444977

ELOA1
Elongin-A

1

1

Small-scale

0.470

High

444959

EYA3
Eyes absent homolog 3

1

0

High-throughput

0.460

High

352954

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

444952

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.458

High

444972

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

444986

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.458

High

444955

CENPC
Centromere protein C

1

3

High-throughput

0.445

High

444958

WDR5
WD repeat-containing protein 5

1

2

Small-scale

0.445

High

444963

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

Small-scale

0.445

High

444967

HIRA
Protein HIRA

1

3

Small-scale

0.445

High

444978

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.445

High

444983

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

Small-scale

0.445

High

444989

KAT2A
Histone acetyltransferase KAT2A

1

8

High-throughput

0.445

High

444990

AIRE
Autoimmune regulator

1

6

Small-scale

0.445

High

420384

TNFA
Tumor necrosis factor

1

1

Small-scale

0.437

High

444982

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.426

High

444957

RUVB1
RuvB-like 1

1

9

Small-scale

0.407

High

444954

CXL10
C-X-C motif chemokine 10

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024