Protein: SLD5
DNA replication complex GINS protein SLD5

Gene: SLD5
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: Q03406

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication
GO:0006268 - DNA unwinding involved in DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

964866

CTF4
DNA polymerase alpha-binding protein

20

1

Small-scale

0.990

High

976281

PSF1
DNA replication complex GINS protein PSF1

21

4

Small-scale

0.989

High

976275

CDC45
Cell division control protein 45

22

3

Small-scale

0.989

High

772609

PSF2
DNA replication complex GINS protein PSF2

17

6

Small-scale

0.985

High

622191

MCM3
DNA replication licensing factor MCM3

18

15

Small-scale

0.983

High

667884

MCM5
Minichromosome maintenance protein 5

16

15

Small-scale

0.983

High

744790

MCM7
DNA replication licensing factor MCM7

14

15

Small-scale

0.982

High

976279

PSF3
DNA replication complex GINS protein PSF3

13

4

Small-scale

0.980

High

675553

MCM4
DNA replication licensing factor MCM4

13

15

Small-scale

0.979

High

859011

MCM6
DNA replication licensing factor MCM6

13

16

Small-scale

0.975

High

667627

MCM2
DNA replication licensing factor MCM2

11

15

Small-scale

0.970

High

976269

SLD5
DNA replication complex GINS protein SLD5

5

0

Small-scale

0.860

High

976272

POB3
FACT complex subunit POB3

6

1

Small-scale

0.721

High

976273

CSM3
Chromosome segregation in meiosis protein 3

11

0

Small-scale

0.721

High

602374

DPOE
DNA polymerase epsilon catalytic subunit A

5

7

Small-scale

0.702

High

526861

DPOLA
DNA polymerase alpha catalytic subunit A

10

7

Small-scale

0.686

High

622891

DPB2
DNA polymerase epsilon subunit B

4

1

Small-scale

0.676

High

634896

MRC1
Mediator of replication checkpoint protein 1

5

0

Small-scale

0.672

High

692896

SPT16
FACT complex subunit SPT16

4

0

Small-scale

0.643

High

688667

MCM10
Minichromosome maintenance protein 10

3

2

Small-scale

0.633

High

865229

TOF1
Topoisomerase 1-associated factor 1

3

1

Small-scale

0.633

High

976277

DIA2
Protein DIA2

3

0

Small-scale

0.613

High

607330

RFA1
Replication factor A protein 1

2

1

Small-scale

0.611

High

355613

H2B1
Histone H2B.1

2

1

Small-scale

0.571

High

355990

H2B2
Histone H2B.2

2

1

Small-scale

0.571

High

976278

CDC53
Cell division control protein 53

2

0

Small-scale

0.569

High

388122

TOP1
DNA topoisomerase 1

2

0

Small-scale

0.559

High

858700

UFD1
Ubiquitin fusion degradation protein 1

2

0

Small-scale

0.559

High

356683

H4
Histone H4

2

0

Small-scale

0.547

High

646641

DPB3
DNA polymerase epsilon subunit C

2

0

Small-scale

0.547

High

810651

DPB11
DNA replication regulator DPB11

1

0

Small-scale

0.537

High

747529

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.486

High

565754

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

811006

CUL8
Cullin-8

1

1

High-throughput

0.479

High

976280

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

636725

CDC48
Cell division control protein 48

1

0

Small-scale

0.458

High

707246

NPL4
Nuclear protein localization protein 4

1

0

Small-scale

0.458

High

711178

SLD2
DNA replication regulator SLD2

1

0

Small-scale

0.458

High

853160

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.458

High

863168

NRD1
Protein NRD1

1

0

Small-scale

0.458

High

959996

SEN1
Helicase SEN1

1

0

Small-scale

0.458

High

976274

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

976276

RBX1
RING-box protein HRT1

1

0

Small-scale

0.458

High

512510

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

769312

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

488499

PRI1
DNA primase small subunit

1

0

Small-scale

0.426

High

593812

PRI2
DNA primase large subunit

1

0

Small-scale

0.426

High

680962

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

695398

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.426

High

744531

DPOA2
DNA polymerase alpha subunit B

1

0

Small-scale

0.426

High

976271

DPB4
DNA polymerase epsilon subunit D

1

0

Small-scale

0.426

High

972958

YP077
Uncharacterized protein YPL077C

2

0

High-throughput

0.323

High

976270

SRC1
Inner nuclear membrane protein SRC1

2

0

High-throughput

0.317

High

746454

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.282

High

798040

IRC6
Increased recombination centers protein 6

1

0

High-throughput

0.265

Low

579844

PGTB1
Geranylgeranyl transferase type-1 subunit beta

1

0

Small-scale

0.249

Low

969459

TOF2
Topoisomerase 1-associated factor 2

1

0

Small-scale

0.249

Low

864722

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.238

Low

692608

ZUO1
Zuotin

1

0

High-throughput

0.232

Low

775654

DJP1
DnaJ-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024