Protein: RRP42
Exosome complex component RRP42 (Ribosomal RNA-processing protein 42)

Gene: RRP42
Organism: Saccharomyces cerevisiae S288C
Interactions: 88
UniProt ID: Q12277

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993688

RRP44
Exosome complex exonuclease DIS3

11

19

Small-scale

0.757

High

816991

MTR3
Exosome complex component MTR3

9

2

Small-scale

0.757

High

1015129

RRP6
Exosome complex exonuclease RRP6

12

10

Small-scale

0.756

High

865438

CSL4
Exosome complex component CSL4

10

11

Small-scale

0.754

High

860829

RRP46
Exosome complex component RRP46

10

20

Small-scale

0.754

High

809605

RRP41
Exosome complex component SKI6

8

20

Small-scale

0.748

High

995869

SKI7
Superkiller protein 7

7

7

Small-scale

0.743

High

984328

RRP45
Exosome complex component RRP45

6

17

Small-scale

0.730

High

755015

RRP4
Exosome complex component RRP4

5

20

Small-scale

0.714

High

630294

RRP43
Exosome complex component RRP43

5

2

Small-scale

0.712

High

864447

MPP6
M-phase phosphoprotein 6 homolog

4

2

Small-scale

0.696

High

994588

RRP40
Exosome complex component RRP40

3

11

Small-scale

0.656

High

748748

ENP1
Essential nuclear protein 1

3

2

High-throughput

0.640

High

979083

DHR1
Probable ATP-dependent RNA helicase DHR1

3

2

High-throughput

0.640

High

571925

SKI3
Superkiller protein 3

2

4

High-throughput

0.611

High

716009

UTP20
U3 small nucleolar RNA-associated protein 20

2

2

High-throughput

0.611

High

634828

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.584

High

792632

UTP10
U3 small nucleolar RNA-associated protein 10

2

2

High-throughput

0.584

High

979750

UTP14
U3 small nucleolar RNA-associated protein 14

2

3

High-throughput

0.584

High

987696

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

982920

RRP5
rRNA biogenesis protein RRP5

2

5

High-throughput

0.571

High

513215

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

769807

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

585392

MYO2
Myosin-2

2

1

High-throughput

0.537

High

811674

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

4

High-throughput

0.536

High

859462

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.518

High

972939

IMA1
Importin subunit alpha

1

2

High-throughput

0.515

High

477491

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

409868

NOT2
General negative regulator of transcription subunit 2

1

2

Small-scale

0.479

High

630563

RRP7
Ribosomal RNA-processing protein 7

1

2

High-throughput

0.479

High

635671

PWP2
Periodic tryptophan protein 2

1

8

High-throughput

0.479

High

663681

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

707161

DCA13
Protein SOF1

1

5

High-throughput

0.479

High

711092

UTP11
U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.479

High

713727

NOT4
General negative regulator of transcription subunit 4

1

1

Small-scale

0.479

High

728342

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

755219

LRP1
Exosome complex protein LRP1

1

2

High-throughput

0.479

High

756812

UTP9
U3 small nucleolar RNA-associated protein 9

1

2

High-throughput

0.479

High

767444

UTP7
U3 small nucleolar RNA-associated protein 7

1

2

High-throughput

0.479

High

772701

UTP18
U3 small nucleolar RNA-associated protein 18

1

3

High-throughput

0.479

High

775408

FAF1
Protein FAF1

1

2

High-throughput

0.479

High

784542

DIM1
Dimethyladenosine transferase

1

1

High-throughput

0.479

High

810956

MTR4
ATP-dependent RNA helicase DOB1

1

13

High-throughput

0.479

High

811580

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

2

High-throughput

0.479

High

816927

NOL10
Ribosome biogenesis protein ENP2

1

1

High-throughput

0.479

High

860776

UTP22
U3 small nucleolar RNA-associated protein 22

1

3

High-throughput

0.479

High

861053

UTP8
U3 small nucleolar RNA-associated protein 8

1

2

High-throughput

0.479

High

861147

CF130
Protein CAF130

1

1

Small-scale

0.479

High

866087

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

866562

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

866638

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

970490

UTP6
U3 small nucleolar RNA-associated protein 6

1

2

High-throughput

0.479

High

973698

UTP17
NET1-associated nuclear protein 1

1

14

High-throughput

0.479

High

978653

UTP5
U3 small nucleolar RNA-associated protein 5

1

7

High-throughput

0.479

High

979265

UTP15
U3 small nucleolar RNA-associated protein 15

1

4

High-throughput

0.479

High

983785

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

985443

UTP13
U3 small nucleolar RNA-associated protein 13

1

8

High-throughput

0.479

High

985836

UTP21
U3 small nucleolar RNA-associated protein 21

1

12

High-throughput

0.479

High

986771

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

2

High-throughput

0.479

High

987621

RRP9
Ribosomal RNA-processing protein 9

1

8

High-throughput

0.479

High

988490

BFR2
Protein BFR2

1

2

High-throughput

0.479

High

988657

UTP4
U3 small nucleolar RNA-associated protein 4

1

8

High-throughput

0.479

High

993376

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

2

High-throughput

0.479

High

995876

UTP16
U3 small nucleolar RNA-associated protein 16

1

2

High-throughput

0.479

High

997066

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

1014906

FCF2
rRNA-processing protein FCF2

1

2

High-throughput

0.479

High

1015084

SAS10
Something about silencing protein 10

1

3

High-throughput

0.479

High

1015331

UTP12
U3 small nucleolar RNA-associated protein 12

1

11

High-throughput

0.479

High

1015408

RRP42
Exosome complex component RRP42

1

18

Small-scale

0.479

High

1015409

NOP56
Nucleolar protein 56

1

7

High-throughput

0.479

High

1015410

NOP58
Nucleolar protein 58

1

7

High-throughput

0.479

High

1015411

RRP12
Ribosomal RNA-processing protein 12

1

2

High-throughput

0.479

High

1015413

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.479

High

733618

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

774297

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

1015172

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

356790

H4
Histone H4

1

1

High-throughput

0.445

High

376977

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

High-throughput

0.445

High

495310

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

634211

SRO9
RNA-binding protein SRO9

1

1

High-throughput

0.445

High

471848

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.437

High

424767

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.407

High

705811

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

837390

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.407

High

713186

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

0

High-throughput

0.269

Low

762672

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1015412

RS22B
Small ribosomal subunit protein uS8B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024