Protein: KIN28
Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)

Gene: KIN28
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P06242

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005675 - transcription factor TFIIH holo complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

412463

CCL1
Cyclin CCL1

12

20

Small-scale

0.979

High

412482

TFB3
RNA polymerase II transcription factor B subunit 3

10

7

Small-scale

0.975

High

412477

PCL10
PHO85 cyclin-10

2

12

High-throughput

0.801

High

412476

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

20

Small-scale

0.781

High

412473

CAK1
Serine/threonine-protein kinase CAK1

2

15

Small-scale

0.778

High

375199

RPB1
DNA-directed RNA polymerase II subunit RPB1

12

9

Small-scale

0.760

High

412435

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

7

3

Small-scale

0.737

High

412485

SSL1
General transcription and DNA repair factor IIH subunit SSL1

3

3

Small-scale

0.662

High

412451

RAD23
UV excision repair protein RAD23

1

9

High-throughput

0.647

High

412475

DPH4
Diphthamide biosynthesis protein 4

1

7

High-throughput

0.647

High

412491

CMR3
Zinc finger protein CRM3

1

1

High-throughput

0.647

High

412493

ARP8
Actin-like protein ARP8

1

10

High-throughput

0.647

High

412488

TFB4
General transcription and DNA repair factor IIH subunit TFB4

3

1

Small-scale

0.643

High

412452

TFB1
General transcription and DNA repair factor IIH subunit TFB1

3

2

Small-scale

0.624

High

409872

CDC37
Hsp90 co-chaperone Cdc37

1

10

Small-scale

0.621

High

412437

SWI6
Regulatory protein SWI6

1

3

High-throughput

0.618

High

412449

HOG1
Mitogen-activated protein kinase HOG1

1

19

Small-scale

0.618

High

412444

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

Small-scale

0.614

High

412480

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

2

8

Small-scale

0.595

High

412474

BUD4
Bud site selection protein 4

1

1

High-throughput

0.579

High

412466

CAJ1
Protein CAJ1

1

2

High-throughput

0.575

High

412492

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

Small-scale

0.569

High

412436

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

Small-scale

0.561

High

412446

URA7
CTP synthase 1

1

4

High-throughput

0.561

High

412469

SSB2
Ribosome-associated molecular chaperone SSB2

2

17

High-throughput

0.552

High

412442

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.547

High

412494

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.536

High

412484

HNT1
Adenosine 5'-monophosphoramidase HNT1

1

0

Small-scale

0.529

High

412453

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

High-throughput

0.512

High

357424

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.501

High

412440

SYFB
Phenylalanine--tRNA ligase beta subunit

1

1

High-throughput

0.501

High

412441

PCNA
Proliferating cell nuclear antigen

1

7

High-throughput

0.501

High

412443

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.501

High

412448

ATS1
Protein KTI13

1

1

High-throughput

0.501

High

412454

DRS1
ATP-dependent RNA helicase DRS1

1

7

High-throughput

0.501

High

412456

UBX1
UBX domain-containing protein 1

1

3

High-throughput

0.501

High

412457

RRP1
Ribosomal RNA-processing protein 1

1

3

High-throughput

0.501

High

412465

TCPZ
T-complex protein 1 subunit zeta

1

17

High-throughput

0.501

High

412471

ATG3
Autophagy-related protein 3

1

1

High-throughput

0.501

High

412489

YTM1
Ribosome biogenesis protein YTM1

1

11

High-throughput

0.501

High

412495

H2AZ
Histone H2A.Z

1

6

High-throughput

0.501

High

412472

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

5

High-throughput

0.489

High

412445

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.480

High

412462

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.480

High

412467

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.480

High

412468

VHR2
Transcription factor VHR2

1

0

High-throughput

0.480

High

412470

RT106
Histone chaperone RTT106

1

0

High-throughput

0.480

High

412478

YG1D
Probable transcriptional regulatory protein HAH1

1

0

High-throughput

0.480

High

412486

YL287
Uncharacterized protein YLR287C

1

0

High-throughput

0.480

High

412490

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

High-throughput

0.480

High

412447

TF2B
Transcription initiation factor IIB

1

7

High-throughput

0.479

High

412458

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.479

High

412481

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

3

High-throughput

0.479

High

412479

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

Small-scale

0.458

High

412483

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

412487

YO352
Uncharacterized protein YOR352W

1

0

High-throughput

0.458

High

412438

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

412439

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.445

High

412450

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

412459

T2EA
Transcription initiation factor IIE subunit alpha

1

1

Small-scale

0.445

High

412460

SET3
SET domain-containing protein 3

1

5

High-throughput

0.445

High

412461

T2EB
Transcription initiation factor IIE subunit beta

1

1

Small-scale

0.445

High

412455

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

Small-scale

0.426

High

412464

SCO2
Protein SCO2, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024