Protein: NACA
Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (GAL4 DNA-binding enhancer protein 2)

Gene: NACA, EGD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 125
UniProt ID: P38879

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005854 - nascent polypeptide-associated complex
GO:0006612 - protein targeting to membrane
GO:0006613 - cotranslational protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

756709

NACB1
Nascent polypeptide-associated complex subunit beta-1

12

20

Small-scale

0.980

High

756680

NACB2
Nascent polypeptide-associated complex subunit beta-2

3

20

Small-scale

0.845

High

756669

NACA
Nascent polypeptide-associated complex subunit alpha

1

4

Small-scale

0.621

High

534987

RL3
Large ribosomal subunit protein uL3

3

0

High-throughput

0.606

High

756722

SMT3
Ubiquitin-like protein SMT3

2

3

High-throughput

0.600

High

498923

RL4A
Large ribosomal subunit protein uL4A

2

1

Small-scale

0.585

High

756688

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

399461

RLA0
Large ribosomal subunit protein uL10

2

1

High-throughput

0.571

High

756697

CF130
Protein CAF130

2

0

High-throughput

0.563

High

756720

TMA46
Translation machinery-associated protein 46

2

0

High-throughput

0.559

High

491190

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.552

High

493941

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

511279

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

624083

DBP2
ATP-dependent RNA helicase DBP2

2

0

High-throughput

0.547

High

741226

GLYM
Serine hydroxymethyltransferase, mitochondrial

2

0

High-throughput

0.547

High

687580

DBF20
Serine/threonine-protein kinase DBF20

1

1

High-throughput

0.536

High

756705

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.536

High

756713

ERB1
Ribosome biogenesis protein ERB1

1

1

High-throughput

0.536

High

450434

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

1

High-throughput

0.521

High

756687

BUD27
Bud site selection protein 27

1

0

Small-scale

0.518

High

392427

H2A2
Histone H2A.2

1

1

High-throughput

0.515

High

485520

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.515

High

756712

HMO1
High mobility group protein 1

1

1

High-throughput

0.515

High

756721

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.515

High

664455

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

549812

UBC4
Ubiquitin-conjugating enzyme E2 4

1

1

Small-scale

0.508

High

549856

UBC5
Ubiquitin-conjugating enzyme E2-16 kDa

1

1

Small-scale

0.508

High

756675

RSP5
E3 ubiquitin-protein ligase RSP5

1

4

Small-scale

0.501

High

420124

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.493

High

756672

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.493

High

756678

SIP5
Protein SIP5

1

0

High-throughput

0.493

High

756701

SYC
Cysteine--tRNA ligase

1

0

High-throughput

0.493

High

756723

SPSY
Spermine synthase SPE4

1

0

High-throughput

0.486

High

756682

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.481

High

756710

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

756724

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.481

High

410375

SC160
Protein SCP160

1

2

High-throughput

0.479

High

477276

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

543712

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

606003

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

729908

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

756706

NOP3
Serine/arginine

1

1

High-throughput

0.479

High

756708

ABF2
ARS-binding factor 2, mitochondrial

1

1

High-throughput

0.479

High

756711

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

756695

SAM37
Sorting assembly machinery 37 kDa subunit

1

0

Small-scale

0.460

High

482258

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

498518

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

526726

PYRE
Orotate phosphoribosyltransferase 1

1

0

High-throughput

0.458

High

628036

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

631872

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

662194

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688235

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

698795

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

752008

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.458

High

753385

ECM29
Proteasome component ECM29

1

0

High-throughput

0.458

High

753799

RPN1
26S proteasome regulatory subunit RPN1

1

0

Small-scale

0.458

High

756670

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

756671

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.458

High

756674

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

756681

TM108
Protein TMA108

1

0

High-throughput

0.458

High

756683

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

756691

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

756696

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

756698

H1
Histone H1

1

0

High-throughput

0.458

High

756699

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

756707

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

756716

HEL2
E3 ubiquitin-protein ligase HEL2

1

0

High-throughput

0.458

High

756717

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

376782

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.445

High

404580

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.445

High

405187

RL17A
Large ribosomal subunit protein uL22A

1

1

Small-scale

0.445

High

694680

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

742788

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.445

High

756677

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

756685

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.445

High

756693

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

541709

SEC63
Protein translocation protein SEC63

1

1

Small-scale

0.439

High

406528

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

425946

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

472186

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

645437

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

737164

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

756684

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

756704

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.437

High

756718

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

368049

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

407041

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

407911

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.426

High

571892

SKI3
Superkiller protein 3

1

0

High-throughput

0.426

High

640943

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

644886

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.426

High

696142

SWI3
SWI/SNF complex subunit SWI3

1

0

High-throughput

0.426

High

756676

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

756694

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

756700

CAF40
Protein CAF40

1

0

Small-scale

0.426

High

756715

RQC1
Ribosome quality control complex subunit 1

1

0

Small-scale

0.426

High

756689

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.407

High

756692

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.407

High

592898

SRP54
Signal recognition particle subunit SRP54

3

0

Small-scale

0.337

High

748486

OM14
Mitochondrial outer membrane protein OM14

2

0

Small-scale

0.323

High

482869

RL35A
Large ribosomal subunit protein uL29A

2

0

Small-scale

0.305

High

706266

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.298

High

580821

GAP1
General amino-acid permease GAP1

1

0

Small-scale

0.288

High

756703

SLG1
Protein SLG1

1

0

Small-scale

0.288

High

710674

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

756673

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

733820

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.269

Low

756690

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.269

Low

756714

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.269

Low

731407

MID2
Cell wall integrity sensor MID2

1

0

Small-scale

0.251

Low

357498

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.249

Low

383140

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405997

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

413499

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

471050

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

645028

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

752033

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

756702

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

756719

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

358061

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.232

Low

479471

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.232

Low

667177

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

756679

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.232

Low

756686

BNI1
Protein BNI1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024