Protein: COPB
Coatomer subunit beta (Beta-coat protein) (Beta-COP)

Gene: COPB, SEC26
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: P41810

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0006886 - intracellular protein transport
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

784341

COPA
Coatomer subunit alpha

10

6

Small-scale

0.974

High

784325

COPB2
Coatomer subunit beta'

7

6

Small-scale

0.963

High

784330

COPD
Coatomer subunit delta

7

2

Small-scale

0.960

High

784340

COPZ
Coatomer subunit zeta

4

20

High-throughput

0.903

High

685539

COPG
Coatomer subunit gamma

4

17

Small-scale

0.892

High

503102

ARF1
ADP-ribosylation factor 1

2

20

Small-scale

0.768

High

751980

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

5

12

Small-scale

0.706

High

784354

ERV41
ER-derived vesicles protein ERV41

4

5

High-throughput

0.694

High

774837

COPE
Coatomer subunit epsilon

5

0

Small-scale

0.682

High

784357

VPS74
Vacuolar protein sorting-associated protein 74

2

5

Small-scale

0.602

High

611782

BET1
Protein transport protein BET1

2

2

Small-scale

0.576

High

784366

RBD2
Rhomboid-type serine protease 2

1

3

High-throughput

0.541

High

715345

SPT7
Transcriptional activator SPT7

1

6

High-throughput

0.536

High

543925

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.533

High

784328

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.533

High

784351

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.518

High

768683

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.504

High

744635

TAF5
Transcription initiation factor TFIID subunit 5

1

3

High-throughput

0.489

High

774473

MOB1
DBF2 kinase activator protein MOB1

1

2

High-throughput

0.489

High

784342

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.489

High

784350

GCN5
Histone acetyltransferase GCN5

1

8

High-throughput

0.489

High

761454

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

Small-scale

0.480

High

784331

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

0

Small-scale

0.480

High

784338

MST27
Multicopy suppressor of SEC21 protein 27

1

0

Small-scale

0.480

High

605855

SEC22
Protein transport protein SEC22

1

2

Small-scale

0.479

High

746005

ATG8
Autophagy-related protein 8

1

3

High-throughput

0.479

High

753353

GOSR1
Golgi SNAP receptor complex member 1

1

1

High-throughput

0.479

High

763770

ERV46
ER-derived vesicles protein ERV46

1

5

High-throughput

0.479

High

774415

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.479

High

784334

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

784359

VAM6
Vacuolar morphogenesis protein 6

1

5

High-throughput

0.479

High

450319

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.470

High

700944

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

784343

DSL1
Protein transport protein DSL1

1

0

High-throughput

0.458

High

784369

SEC39
Protein transport protein SEC39

1

0

Small-scale

0.458

High

682236

OCH1
Initiation-specific alpha-1,6-mannosyltransferase

1

1

Small-scale

0.457

High

731636

MNN4
Protein MNN4

1

10

Small-scale

0.457

High

778731

CDC1
Cell division control protein 1

1

1

Small-scale

0.457

High

503007

SEC7
Protein transport protein SEC7

1

4

Small-scale

0.445

High

471111

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

491536

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.437

High

622169

MCM3
DNA replication licensing factor MCM3

1

3

High-throughput

0.437

High

697953

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

4

Small-scale

0.437

High

728263

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.437

High

729962

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

730832

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

742847

GBLP
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.437

High

752507

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

753411

ECM29
Proteasome component ECM29

1

1

High-throughput

0.437

High

753851

RPN1
26S proteasome regulatory subunit RPN1

1

4

High-throughput

0.437

High

756953

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

762295

LAA1
AP-1 accessory protein LAA1

1

5

High-throughput

0.437

High

774307

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

4

High-throughput

0.437

High

784327

LAM5
Membrane-anchored lipid-binding protein LAM5

1

3

High-throughput

0.437

High

784329

ATG18
Autophagy-related protein 18

1

2

High-throughput

0.437

High

784339

CDH1
APC/C activator protein CDH1

1

7

Small-scale

0.437

High

784346

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.437

High

784348

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

784353

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.437

High

784362

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.437

High

784367

CEX1
Cytoplasmic export protein 1

1

8

High-throughput

0.437

High

784368

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.437

High

784370

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.437

High

784345

TMEDA
Endoplasmic reticulum vesicle protein 25

1

7

Small-scale

0.408

High

703916

PRS7
26S proteasome regulatory subunit 7 homolog

1

4

High-throughput

0.407

High

784352

WDR59
Maintenance of telomere capping protein 5

1

9

High-throughput

0.407

High

735337

RM10
Large ribosomal subunit protein uL15m

2

0

High-throughput

0.324

High

747881

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

2

0

High-throughput

0.307

High

536697

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

682284

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.282

High

693411

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.282

High

703984

SUR1
Mannosyl phosphorylinositol ceramide synthase SUR1

1

0

High-throughput

0.282

High

732826

AUR1
Inositol phosphorylceramide synthase catalytic subunit AUR1

1

0

High-throughput

0.282

High

743567

HMT1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.282

High

784326

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.282

High

753147

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.279

Low

767785

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.279

Low

784347

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.279

Low

784361

MCA1
Metacaspase-1

1

0

Small-scale

0.279

Low

746680

FMP23
Protein FMP23, mitochondrial

1

0

High-throughput

0.269

Low

784335

PIP2
Peroxisome proliferation transcriptional regulator

1

0

High-throughput

0.269

Low

784364

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.269

Low

744741

KTR3
Probable mannosyltransferase KTR3

1

0

Small-scale

0.261

Low

358115

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

402970

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.249

Low

405677

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

407117

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

628176

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

638787

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

662501

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

680789

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

688605

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

0

High-throughput

0.249

Low

706329

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

733709

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.249

Low

747584

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.249

Low

755056

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

762180

ATC3
Phospholipid-transporting ATPase DRS2

1

0

Small-scale

0.249

Low

765290

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.249

Low

784332

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

784333

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

784336

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.249

Low

784344

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

784349

ESP1
Separin

1

0

High-throughput

0.249

Low

784355

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

784356

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

784358

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.249

Low

784360

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

784363

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

784365

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

Small-scale

0.249

Low

452551

KEX1
Pheromone-processing carboxypeptidase KEX1

1

0

High-throughput

0.238

Low

748242

FTH1
Iron transporter FTH1

1

0

High-throughput

0.238

Low

540595

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

561245

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.232

Low

690574

DPH5
Diphthine methyl ester synthase

1

0

High-throughput

0.232

Low

745386

SEA4
SEH-associated protein 4

1

0

High-throughput

0.232

Low

757428

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low

784337

RRT6
Regulator of rDNA transcription protein 6

1

0

Small-scale

0.213

Low


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Last updated: 15 Jul 2024