Protein: SMC5
Structural maintenance of chromosomes protein 5

Gene: SMC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: Q08204

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000725 - recombinational repair
GO:0000781 - chromosome, telomeric region
GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

994048

SMC6
Structural maintenance of chromosomes protein 6

10

17

Small-scale

0.972

High

751455

NSE2
E3 SUMO-protein ligase MMS21

12

1

Small-scale

0.762

High

793577

NSE4
Non-structural maintenance of chromosome element 4

9

9

Small-scale

0.752

High

767105

KRE29
DNA repair protein KRE29

9

1

Small-scale

0.751

High

984148

NSE3
Non-structural maintenance of chromosome element 3

7

1

Small-scale

0.746

High

775585

MPH1
ATP-dependent DNA helicase MPH1

6

11

Small-scale

0.742

High

977399

NSE5
Non-structural maintenance of chromosome element 5

5

1

Small-scale

0.716

High

992615

NSE1
Non-structural maintenance of chromosomes element 1

5

1

Small-scale

0.716

High

756216

RT107
Regulator of Ty1 transposition protein 107

4

11

Small-scale

0.699

High

994046

SMT3
Ubiquitin-like protein SMT3

4

12

Small-scale

0.685

High

715658

SGS1
ATP-dependent helicase SGS1

3

8

Small-scale

0.661

High

978330

SCC2
Sister chromatid cohesion protein 2

1

9

High-throughput

0.618

High

765594

SAP1
Protein SAP1

2

2

High-throughput

0.595

High

979645

SPC24
Kinetochore protein SPC24

2

1

High-throughput

0.595

High

994050

CENPS
Inner kinetochore subunit MHF1

1

0

Small-scale

0.537

High

767748

IMB4
Importin subunit beta-4

1

2

High-throughput

0.515

High

454481

TBA1
Tubulin alpha-1 chain

1

16

Small-scale

0.501

High

798295

CHA4
Activatory protein CHA4

1

0

High-throughput

0.486

High

987172

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

523455

SRS2
ATP-dependent DNA helicase SRS2

1

3

Small-scale

0.481

High

605702

KIN3
Serine/threonine-protein kinase KIN3

1

20

High-throughput

0.481

High

708069

NUF2
Kinetochore protein NUF2

1

7

High-throughput

0.481

High

812441

NNF1
Kinetochore-associated protein NNF1

1

2

High-throughput

0.481

High

994049

CENPX
Inner kinetochore subunit MHF2

1

0

Small-scale

0.480

High

525788

TOP3
DNA topoisomerase 3

1

2

Small-scale

0.479

High

602383

DPOE
DNA polymerase epsilon catalytic subunit A

1

3

Small-scale

0.479

High

663501

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

866521

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

987945

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

622901

DPB2
DNA polymerase epsilon subunit B

1

0

Small-scale

0.458

High

746164

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

994044

SLX4
Structure-specific endonuclease subunit SLX4

1

0

Small-scale

0.458

High

361053

TBB
Tubulin beta chain

1

13

Small-scale

0.457

High

366996

HSP82
ATP-dependent molecular chaperone HSP82

1

14

High-throughput

0.445

High

492637

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

695661

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

754760

SSZ1
Ribosome-associated complex subunit SSZ1

1

10

High-throughput

0.445

High

766244

HSP7E
Heat shock protein SSC3, mitochondrial

1

14

High-throughput

0.445

High

769642

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

858910

VID30
Vacuolar import and degradation protein 30

1

12

High-throughput

0.445

High

759276

END3
Actin cytoskeleton-regulatory complex protein END3

1

6

High-throughput

0.439

High

744342

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.437

High

743497

EDS1
Transcriptional regulatory protein EDS1

1

0

High-throughput

0.426

High

977705

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

985480

ECM22
Sterol regulatory element-binding protein ECM22

1

0

High-throughput

0.426

High

520880

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.407

High

572064

CLC1
Clathrin light chain

1

3

High-throughput

0.407

High

707942

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.407

High

994047

HSP42
Heat shock protein 42

1

3

High-throughput

0.407

High

704494

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.269

Low

613143

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.265

Low

715907

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.265

Low

973011

MUK1
Protein MUK1

1

0

High-throughput

0.265

Low

985871

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.265

Low

994045

HUA2
Protein HUA2

1

0

High-throughput

0.265

Low

763993

HPH2
Protein HPH2

1

0

High-throughput

0.251

Low

602950

KRE5
Killer toxin-resistance protein 5

1

0

High-throughput

0.232

Low

634225

ATG22
Autophagy-related protein 22

1

0

High-throughput

0.232

Low

756464

SVP26
Protein SVP26

1

0

High-throughput

0.232

Low

763446

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.232

Low

992535

YL001
FAS1 domain-containing protein YLR001C

1

0

High-throughput

0.232

Low

994043

FEX1
Fluoride export protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024