Protein: JHD2
Histone demethylase JHD2 (EC 1.14.11.67) (Jumonji/ARID domain-containing protein 2) ([histone H3]-trimethyl-L-lysine(4) demethylase JHD2)

Gene: JHD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P47156

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

812502

JHD2
Histone demethylase JHD2

2

12

Small-scale

0.768

High

812506

H3
Histone H3

5

20

Small-scale

0.710

High

694108

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

Small-scale

0.618

High

812513

YRA1
RNA annealing protein YRA1

1

2

Small-scale

0.618

High

812514

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

2

Small-scale

0.618

High

376840

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.586

High

412999

KAPB
cAMP-dependent protein kinase type 2

1

3

Small-scale

0.561

High

628791

RNA15
mRNA 3'-end-processing protein RNA15

1

1

Small-scale

0.553

High

768846

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

679869

FUN30
ATP-dependent helicase FUN30

1

10

High-throughput

0.515

High

392153

H2A1
Histone H2A.1

1

1

Small-scale

0.501

High

713706

NOT4
General negative regulator of transcription subunit 4

1

2

Small-scale

0.501

High

751045

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.501

High

812507

SKY1
Serine/threonine-protein kinase SKY1

1

3

High-throughput

0.501

High

774723

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.493

High

812512

SAS10
Something about silencing protein 10

1

0

High-throughput

0.493

High

523418

SRS2
ATP-dependent DNA helicase SRS2

1

1

Small-scale

0.481

High

368198

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.479

High

409660

KAPC
cAMP-dependent protein kinase type 3

1

4

Small-scale

0.479

High

412803

KAPA
cAMP-dependent protein kinase type 1

1

4

Small-scale

0.479

High

728152

MPE1
Protein MPE1

1

1

Small-scale

0.479

High

791175

PFS2
Polyadenylation factor subunit 2

1

8

Small-scale

0.479

High

812503

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.479

High

812505

PBP1
PAB1-binding protein 1

1

1

Small-scale

0.479

High

812509

PBP4
Protein PBP4

1

1

Small-scale

0.479

High

425637

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

628763

RNA14
mRNA 3'-end-processing protein RNA14

1

0

Small-scale

0.458

High

650334

SPT5
Transcription elongation factor SPT5

1

0

Small-scale

0.458

High

667528

PAP
Poly(A) polymerase

1

0

Small-scale

0.458

High

755833

LSM12
Protein LSM12

1

0

Small-scale

0.458

High

761130

PCF11
Protein PCF11

1

0

Small-scale

0.458

High

764811

PTI1
Protein PTI1

1

0

Small-scale

0.458

High

785590

REF2
RNA end formation protein 2

1

0

Small-scale

0.458

High

800678

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

Small-scale

0.458

High

812510

SUB2
ATP-dependent RNA helicase SUB2

1

0

Small-scale

0.458

High

812511

CFT2
Cleavage factor two protein 2

1

0

Small-scale

0.458

High

491727

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

494357

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

511887

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

544036

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.445

High

628234

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

695030

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

766089

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

812508

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.445

High

735729

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.249

Low

812504

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024