Protein: NOT2
General negative regulator of transcription subunit 2 (cell division cycle protein 36)

Gene: NOT2, CDC36
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P06100

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000749 - response to pheromone triggering conjugation with cellular fusion
GO:0000932 - P-body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

409824

NOT1
General negative regulator of transcription subunit 1

12

6

Small-scale

0.979

High

409869

NOT5
General negative regulator of transcription subunit 5

8

8

Small-scale

0.974

High

409814

NOT3
General negative regulator of transcription subunit 3

6

8

Small-scale

0.943

High

409813

NOT2
General negative regulator of transcription subunit 2

2

9

Small-scale

0.757

High

409856

CAF40
Protein CAF40

9

7

Small-scale

0.751

High

409833

NOT4
General negative regulator of transcription subunit 4

8

3

Small-scale

0.745

High

409826

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

6

10

Small-scale

0.730

High

409839

POP2
Poly(A) ribonuclease POP2

5

9

Small-scale

0.710

High

409823

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

5

High-throughput

0.541

High

409855

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.536

High

409862

MRD1
Multiple RNA-binding domain-containing protein 1

1

3

High-throughput

0.536

High

409832

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.518

High

409835

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.518

High

409857

ADA2
Transcriptional adapter 2

1

1

Small-scale

0.518

High

409819

TBP
TATA-box-binding protein

1

1

Small-scale

0.515

High

409851

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

2

Small-scale

0.515

High

409859

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

3

Small-scale

0.508

High

409579

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

409840

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

Small-scale

0.486

High

409818

TAF13
Transcription initiation factor TFIID subunit 13

1

1

Small-scale

0.481

High

375195

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.479

High

409820

DBP5
ATP-dependent RNA helicase DBP5

1

2

Small-scale

0.479

High

409822

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

409825

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

409830

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

409834

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

409836

HMT1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.479

High

409844

NACB2
Nascent polypeptide-associated complex subunit beta-2

1

3

High-throughput

0.479

High

409845

RRP41
Exosome complex component SKI6

1

1

Small-scale

0.479

High

409847

MTR4
ATP-dependent RNA helicase DOB1

1

3

Small-scale

0.479

High

409854

CF130
Protein CAF130

1

1

High-throughput

0.479

High

409860

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

409866

YRA1
RNA annealing protein YRA1

1

1

Small-scale

0.479

High

409868

RRP42
Exosome complex component RRP42

1

2

Small-scale

0.479

High

409871

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

4

Small-scale

0.479

High

409827

MSB2
Signaling mucin MSB2

1

3

High-throughput

0.464

High

409821

DBF2
Cell cycle protein kinase DBF2

1

0

Small-scale

0.460

High

409842

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

409816

METK1
S-adenosylmethionine synthase 1

1

0

Small-scale

0.458

High

409829

NUP2
Nucleoporin NUP2

1

0

Small-scale

0.458

High

409831

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.458

High

409848

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

409863

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

409867

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

409837

GIC1
GTPase-interacting component 1

1

1

High-throughput

0.457

High

409815

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

409817

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

409843

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

409850

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.438

High

409865

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.438

High

409849

YJY1
Uncharacterized protein YJR011C

1

1

High-throughput

0.437

High

409858

MLP1
Protein MLP1

1

1

Small-scale

0.437

High

409864

GIC2
GTPase-interacting component 2

1

1

High-throughput

0.417

High

409828

ATP11
Protein ATP11, mitochondrial

2

0

High-throughput

0.313

High

409838

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.288

High

409841

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

409852

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

409846

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

409853

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low

409861

GPI19
Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19

1

0

High-throughput

0.238

Low

409870

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024