Protein: SYF1
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)

Gene: SYF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: Q04048

Gene Ontology (top 5):
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

977074

CEF1
Pre-mRNA-splicing factor CEF1

13

13

Small-scale

0.761

High

598647

ISY1
Pre-mRNA-splicing factor ISY1

10

6

Small-scale

0.761

High

692352

PRP19
Pre-mRNA-processing factor 19

12

17

Small-scale

0.760

High

748086

NTC20
Pre-mRNA-splicing factor NTC20

8

1

Small-scale

0.755

High

861073

SYF2
Pre-mRNA-splicing factor SYF2

8

1

Small-scale

0.752

High

978488

CLF1
Pre-mRNA-splicing factor CLF1

8

10

Small-scale

0.752

High

657767

YJU2
Splicing factor YJU2

8

5

Small-scale

0.749

High

655748

PRP45
Pre-mRNA-processing protein 45

7

7

Small-scale

0.746

High

978485

CWC2
Pre-mRNA-splicing factor CWC2

5

7

Small-scale

0.718

High

704713

PRP8
Pre-mRNA-splicing factor 8

5

11

Small-scale

0.714

High

978478

SN309
Pre-mRNA-splicing factor SNT309

4

1

Small-scale

0.697

High

697256

BRR2
Pre-mRNA-splicing helicase BRR2

4

20

Small-scale

0.686

High

978484

RU2A
U2 small nuclear ribonucleoprotein A'

4

9

Small-scale

0.686

High

766955

RSMB
Small nuclear ribonucleoprotein-associated protein B

3

12

High-throughput

0.656

High

978480

SP382
Pre-mRNA-splicing factor SPP382

2

3

Small-scale

0.628

High

733094

NTR2
Pre-mRNA-splicing factor NTR2

2

1

Small-scale

0.611

High

861577

CWC22
Pre-mRNA-splicing factor CWC22

2

2

High-throughput

0.611

High

978489

PRP46
Pre-mRNA-splicing factor PRP46

2

19

High-throughput

0.611

High

795418

SMD3
Small nuclear ribonucleoprotein Sm D3

2

20

High-throughput

0.601

High

622340

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

19

Small-scale

0.595

High

589452

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

19

High-throughput

0.584

High

710215

NCBP1
Nuclear cap-binding protein complex subunit 1

2

3

High-throughput

0.584

High

731769

SN114
Pre-mRNA-splicing factor SNU114

2

14

Small-scale

0.584

High

970237

SMD1
Small nuclear ribonucleoprotein Sm D1

2

3

Small-scale

0.584

High

978483

NCBP2
Nuclear cap-binding protein subunit 2

2

20

High-throughput

0.584

High

865373

CWC25
Pre-mRNA-splicing factor CWC25

2

1

High-throughput

0.571

High

769374

SSB2
Ribosome-associated molecular chaperone SSB2

2

11

High-throughput

0.552

High

977624

VHS1
Serine/threonine-protein kinase VHS1

1

1

High-throughput

0.536

High

681331

TPS2
Trehalose-phosphatase

1

2

High-throughput

0.515

High

764125

RV167
Reduced viability upon starvation protein 167

1

3

High-throughput

0.515

High

809580

RRP41
Exosome complex component SKI6

1

9

High-throughput

0.508

High

978475

SYF1
Pre-mRNA-splicing factor SYF1

1

9

Small-scale

0.508

High

784322

HKR1
Signaling mucin HKR1

1

4

High-throughput

0.494

High

860786

DRN1
CWF19-like protein DRN1

1

1

Small-scale

0.481

High

375497

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

4

Small-scale

0.479

High

554246

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

20

High-throughput

0.479

High

586523

PRP9
Pre-mRNA-splicing factor PRP9

1

3

High-throughput

0.479

High

629394

BUD31
Pre-mRNA-splicing factor BUD31

1

5

High-throughput

0.479

High

663212

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

692429

PRP21
Pre-mRNA-splicing factor PRP21

1

6

High-throughput

0.479

High

746876

SLT11
Pre-mRNA-splicing factor SLT11

1

4

High-throughput

0.479

High

770333

RUXG
Small nuclear ribonucleoprotein G

1

20

High-throughput

0.479

High

775700

IST3
U2 snRNP component IST3

1

12

High-throughput

0.479

High

775724

MSL1
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.479

High

778635

PRP17
Pre-mRNA-processing factor 17

1

20

High-throughput

0.479

High

809548

CWC26
Pre-mRNA-splicing factor CWC26

1

3

High-throughput

0.479

High

836935

SF3B1
U2 snRNP component HSH155

1

9

High-throughput

0.479

High

873663

RUXF
Small nuclear ribonucleoprotein F

1

12

High-throughput

0.479

High

971112

SPP2
Pre-mRNA-splicing factor SPP2

1

1

High-throughput

0.479

High

971691

CUS1
Cold sensitive U2 snRNA suppressor 1

1

3

High-throughput

0.479

High

976125

CWC21
Pre-mRNA-splicing factor CWC21

1

2

High-throughput

0.479

High

977571

CWC15
Pre-mRNA-splicing factor CWC15

1

1

High-throughput

0.479

High

978476

PDS5
Sister chromatid cohesion protein PDS5

1

3

High-throughput

0.479

High

978477

RSE1
Pre-mRNA-splicing factor RSE1

1

4

High-throughput

0.479

High

978479

SMD2
Small nuclear ribonucleoprotein Sm D2

1

6

High-throughput

0.479

High

978481

RDS3
Pre-mRNA-splicing factor RDS3

1

2

High-throughput

0.479

High

978482

PRP11
Pre-mRNA-splicing factor PRP11

1

4

High-throughput

0.479

High

978486

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

978490

HSH49
Protein HSH49

1

7

High-throughput

0.479

High

700211

RT04
Small ribosomal subunit protein uS2m

1

3

High-throughput

0.464

High

704970

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.458

High

492319

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

494868

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

512592

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

628428

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

972388

CWC27
Peptidyl-prolyl isomerase CWC27

1

3

High-throughput

0.437

High

972427

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.437

High

978487

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.426

High

810134

PFD1
Prefoldin subunit 1

1

2

High-throughput

0.407

High

699141

SEC6
Exocyst complex component SEC6

1

0

High-throughput

0.269

Low

744112

ATG42
Vacuolar serine-type carboxypeptidase ATG42

1

0

High-throughput

0.269

Low

711022

MTC2
Maintenance of telomere capping protein 2

1

0

High-throughput

0.265

Low

756477

SSP1
Sporulation-specific protein 1

1

0

High-throughput

0.265

Low

608809

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.261

Low

568907

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.249

Low

629769

STE50
Protein STE50

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024