Protein: IF5
Eukaryotic translation initiation factor 5 (eIF-5)

Gene: IF5, TIF5
Organism: Saccharomyces cerevisiae S288C
Interactions: 88
UniProt ID: P38431

Gene Ontology (top 5):
GO:0001731 - formation of translation preinitiation complex
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005096 - GTPase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701206

SUI1
Eukaryotic translation initiation factor eIF-1

11

3

Small-scale

0.977

High

690917

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

10

10

Small-scale

0.975

High

750126

IF2P
Eukaryotic translation initiation factor 5B

3

4

High-throughput

0.855

High

691740

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

11

Small-scale

0.768

High

691536

EIF3C
Eukaryotic translation initiation factor 3 subunit C

17

3

Small-scale

0.766

High

410115

EIF3B
Eukaryotic translation initiation factor 3 subunit B

15

5

Small-scale

0.762

High

447184

IF2B
Eukaryotic translation initiation factor 2 subunit beta

12

8

Small-scale

0.760

High

750130

EIF3I
Eukaryotic translation initiation factor 3 subunit I

12

6

Small-scale

0.759

High

593843

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

10

7

Small-scale

0.755

High

746975

EIF3A
Eukaryotic translation initiation factor 3 subunit A

7

6

Small-scale

0.746

High

750148

EIF3G
Eukaryotic translation initiation factor 3 subunit G

4

4

Small-scale

0.691

High

750150

EIF3J
Eukaryotic translation initiation factor 3 subunit J

5

0

Small-scale

0.684

High

680664

HS104
Heat shock protein 104

3

3

Small-scale

0.640

High

750127

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

3

Small-scale

0.629

High

750146

RLI1
Translation initiation factor RLI1

2

1

High-throughput

0.621

High

750141

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.618

High

750129

SSB2
Ribosome-associated molecular chaperone SSB2

3

4

High-throughput

0.611

High

407013

RS3
Small ribosomal subunit protein uS3

2

3

High-throughput

0.611

High

750144

NOG1
Nucleolar GTP-binding protein 1

2

1

High-throughput

0.588

High

662098

TF2B
Transcription initiation factor IIB

3

2

High-throughput

0.587

High

543656

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

750132

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

6

High-throughput

0.584

High

750153

ATG9
Autophagy-related protein 9

2

1

High-throughput

0.567

High

750136

LSG1
Large subunit GTPase 1

2

0

High-throughput

0.563

High

750128

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

5

Small-scale

0.561

High

491076

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

493847

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

407512

RS9B
Small ribosomal subunit protein uS4B

1

3

High-throughput

0.536

High

511149

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.536

High

520604

YPK1
Serine/threonine-protein kinase YPK1

1

4

High-throughput

0.536

High

645017

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.536

High

645200

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.536

High

645412

RS7A
Small ribosomal subunit protein eS7A

1

5

High-throughput

0.536

High

750135

RS7B
Small ribosomal subunit protein eS7B

1

5

High-throughput

0.536

High

750142

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.536

High

750154

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.536

High

627989

SIS1
Protein SIS1

1

5

High-throughput

0.515

High

404564

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.513

High

415963

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.513

High

644876

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

412976

KAPB
cAMP-dependent protein kinase type 2

1

4

Small-scale

0.501

High

584722

CSK22
Casein kinase II subunit alpha'

1

8

Small-scale

0.501

High

691787

EI2BB
Translation initiation factor eIF2B subunit beta

1

16

Small-scale

0.501

High

750124

IF1A
Eukaryotic translation initiation factor 1A

1

1

Small-scale

0.501

High

676013

XPO1
Exportin-1

1

7

High-throughput

0.489

High

383112

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

405591

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

407882

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

408345

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

413477

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.479

High

425920

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.479

High

471024

RS22A
Small ribosomal subunit protein uS8A

1

3

Small-scale

0.479

High

472162

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

479462

RS24A
Small ribosomal subunit protein eS24A

1

1

Small-scale

0.479

High

479733

RS4A
Small ribosomal subunit protein eS4A

1

2

High-throughput

0.479

High

480073

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

481501

RS11B
Small ribosomal subunit protein uS17B

1

3

High-throughput

0.479

High

481629

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

524275

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

700377

RSSA1
Small ribosomal subunit protein uS2A

1

3

Small-scale

0.479

High

750125

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

750147

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

687060

ACH1
Acetyl-CoA hydrolase

1

0

High-throughput

0.458

High

750133

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

498909

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.445

High

633190

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

695956

HSP79
Heat shock protein homolog SSE2

1

6

High-throughput

0.445

High

750131

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.439

High

704663

PRP8
Pre-mRNA-splicing factor 8

1

1

High-throughput

0.437

High

737152

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

745631

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

750122

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.437

High

750123

OTU2
OTU domain-containing protein 2

1

1

Small-scale

0.437

High

750139

COPA
Coatomer subunit alpha

1

3

High-throughput

0.437

High

750145

ESP1
Separin

1

1

High-throughput

0.437

High

406328

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.426

High

705121

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.407

High

750134

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

750151

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

5

High-throughput

0.407

High

650284

SPT5
Transcription elongation factor SPT5

2

0

High-throughput

0.307

High

750138

PESC
Pescadillo homolog

2

0

High-throughput

0.307

High

750143

UTP6
U3 small nucleolar RNA-associated protein 6

2

0

High-throughput

0.307

High

750140

KTR5
Probable mannosyltransferase KTR5

1

0

High-throughput

0.269

Low

614632

KC11
Casein kinase I homolog 1

1

0

Small-scale

0.261

Low

732278

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

750137

VIR
Protein virilizer

1

0

High-throughput

0.249

Low

750152

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

750149

RQC1
Ribosome quality control complex subunit 1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024