Protein: MED11
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)

Gene: MED11
Organism: Saccharomyces cerevisiae S288C
Interactions: 52
UniProt ID: Q99278

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001097 - TFIIH-class transcription factor complex binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693578

MED17
Mediator of RNA polymerase II transcription subunit 17

15

0

Small-scale

0.934

High

693615

MED22
Mediator of RNA polymerase II transcription subunit 22

9

0

Small-scale

0.927

High

693950

MED18
Mediator of RNA polymerase II transcription subunit 18

8

0

Small-scale

0.915

High

748127

MED8
Mediator of RNA polymerase II transcription subunit 8

6

0

Small-scale

0.884

High

994571

MED7
Mediator of RNA polymerase II transcription subunit 7

7

0

Small-scale

0.710

High

581392

MED14
Mediator of RNA polymerase II transcription subunit 14

4

0

Small-scale

0.648

High

704168

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

Small-scale

0.648

High

859251

MED5
Mediator of RNA polymerase II transcription subunit 5

3

0

Small-scale

0.628

High

626049

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.616

High

1015073

MED2
Mediator of RNA polymerase II transcription subunit 2

3

0

High-throughput

0.616

High

1015459

MED1
Mediator of RNA polymerase II transcription subunit 1

2

0

High-throughput

0.585

High

710285

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.576

High

986576

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.576

High

751484

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

Small-scale

0.559

High

420527

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.529

High

774250

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.486

High

784888

T2FB
Transcription initiation factor IIF subunit beta

1

0

Small-scale

0.479

High

389150

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

546231

SYKC
Lysine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

558353

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

586352

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.458

High

686878

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.458

High

687780

BTAF1
TATA-binding protein-associated factor MOT1

1

0

Small-scale

0.458

High

692654

ZUO1
Zuotin

1

0

High-throughput

0.458

High

715769

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.458

High

716534

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

728353

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

732535

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.458

High

754293

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.458

High

754854

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.458

High

758041

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

760606

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

High-throughput

0.458

High

770310

CCS1
Superoxide dismutase 1 copper chaperone

1

0

High-throughput

0.458

High

772536

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.458

High

812192

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

814161

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.458

High

814177

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.458

High

1015188

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1015503

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1015744

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

1303373

IGO2
mRNA stability protein IGO2

1

0

High-throughput

0.458

High

866216

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

992654

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.438

High

994562

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

752893

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.437

High

769929

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

775336

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.282

High

734088

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.251

Low

389026

SYTC
Threonine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

425096

SYH
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

764944

SS120
Protein SSP120

1

0

High-throughput

0.249

Low

797060

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024