Protein: CBF1
Centromere-binding protein 1 (CBP-1) (Centromere promoter factor 1) (Centromere-binding factor 1)

Gene: CBF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P17106

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

565141

CBF1
Centromere-binding protein 1

4

16

Small-scale

0.887

High

565148

MET4
Transcriptional activator of sulfur metabolism MET4

4

0

Small-scale

0.656

High

565149

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

2

1

Small-scale

0.629

High

565160

MET28
Transcriptional activator of sulfur metabolism MET28

2

0

Small-scale

0.579

High

565144

RAD53
Serine/threonine-protein kinase RAD53

2

2

High-throughput

0.576

High

490250

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

565159

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.547

High

565152

CENPC
Inner kinetochore subunit MIF2

1

0

Small-scale

0.537

High

565153

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

Small-scale

0.537

High

565161

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.537

High

565151

RT04
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.515

High

392045

H2A1
Histone H2A.1

1

3

Small-scale

0.501

High

565143

DBF2
Cell cycle protein kinase DBF2

1

2

Small-scale

0.501

High

565146

PSK1
Serine/threonine-protein kinase PSK1

1

2

Small-scale

0.501

High

565163

H3
Histone H3

1

7

Small-scale

0.501

High

498631

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.493

High

565167

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.486

High

514139

NHP6A
Non-histone chromosomal protein 6A

1

15

Small-scale

0.481

High

514230

NHP6B
Non-histone chromosomal protein 6B

1

15

Small-scale

0.481

High

565157

TRA1
Transcription-associated protein 1

1

3

Small-scale

0.481

High

565147

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.480

High

565156

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

10

Small-scale

0.479

High

565165

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.479

High

565142

AFT1
Iron-regulated transcriptional activator AFT1

1

0

Small-scale

0.460

High

557855

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

565145

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

565155

MCR1
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.458

High

565166

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

565169

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

565170

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

565171

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.458

High

493126

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

510169

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

565150

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

565154

CENPA
Histone H3-like centromeric protein CSE4

1

7

Small-scale

0.445

High

565158

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

565164

ELOC
Elongin-C

1

1

Small-scale

0.439

High

565168

MET32
Transcriptional regulator MET32

1

0

Small-scale

0.426

High

516841

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.292

High

565162

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.261

Low

565172

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024