Protein: UTP12
U3 small nucleolar RNA-associated protein 12 (U3 snoRNA-associated protein 12) (DOM34-interacting protein 2) (U three protein 12)

Gene: UTP12, DIP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: Q12220

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635670

PWP2
Periodic tryptophan protein 2

11

15

Small-scale

0.981

High

985442

UTP13
U3 small nucleolar RNA-associated protein 13

9

18

Small-scale

0.976

High

772700

UTP18
U3 small nucleolar RNA-associated protein 18

8

3

Small-scale

0.970

High

985835

UTP21
U3 small nucleolar RNA-associated protein 21

7

18

Small-scale

0.967

High

767443

UTP7
U3 small nucleolar RNA-associated protein 7

4

17

High-throughput

0.900

High

988656

UTP4
U3 small nucleolar RNA-associated protein 4

2

18

Small-scale

0.754

High

987693

NOC4
Nucleolar complex protein 4

8

7

Small-scale

0.747

High

748747

ENP1
Essential nuclear protein 1

7

3

Small-scale

0.742

High

970489

UTP6
U3 small nucleolar RNA-associated protein 6

5

2

Small-scale

0.720

High

979081

DHR1
Probable ATP-dependent RNA helicase DHR1

5

6

Small-scale

0.702

High

865634

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

15

High-throughput

0.698

High

860775

UTP22
U3 small nucleolar RNA-associated protein 22

4

3

High-throughput

0.697

High

864748

ESF2
Pre-rRNA-processing protein ESF2

4

3

Small-scale

0.693

High

1015334

NOP58
Nucleolar protein 58

4

11

Small-scale

0.672

High

756811

UTP9
U3 small nucleolar RNA-associated protein 9

3

2

High-throughput

0.667

High

634825

KRR1
KRR1 small subunit processome component

3

3

High-throughput

0.656

High

792630

UTP10
U3 small nucleolar RNA-associated protein 10

3

4

High-throughput

0.640

High

707160

DCA13
Protein SOF1

1

19

High-throughput

0.618

High

810955

MTR4
ATP-dependent RNA helicase DOB1

1

17

High-throughput

0.618

High

973697

UTP17
NET1-associated nuclear protein 1

1

18

High-throughput

0.618

High

978652

UTP5
U3 small nucleolar RNA-associated protein 5

1

17

High-throughput

0.618

High

979264

UTP15
U3 small nucleolar RNA-associated protein 15

1

18

High-throughput

0.618

High

987620

RRP9
Ribosomal RNA-processing protein 9

1

18

High-throughput

0.618

High

986081

SGD1
Suppressor of glycerol defect protein 1

2

5

High-throughput

0.614

High

775407

FAF1
Protein FAF1

2

2

Small-scale

0.611

High

811579

MPP10
U3 small nucleolar RNA-associated protein MPP10

2

5

Small-scale

0.611

High

630562

RRP7
Ribosomal RNA-processing protein 7

2

2

High-throughput

0.584

High

716008

UTP20
U3 small nucleolar RNA-associated protein 20

2

2

High-throughput

0.584

High

865437

CSL4
Exosome complex component CSL4

2

3

High-throughput

0.584

High

866085

NAT10
RNA cytidine acetyltransferase

2

3

High-throughput

0.584

High

979749

UTP14
U3 small nucleolar RNA-associated protein 14

2

5

High-throughput

0.584

High

997065

BMS1
Ribosome biogenesis protein BMS1

2

6

High-throughput

0.584

High

1015128

RRP6
Exosome complex exonuclease RRP6

2

5

High-throughput

0.584

High

860416

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.553

High

985915

MRD1
Multiple RNA-binding domain-containing protein 1

1

9

Small-scale

0.536

High

769791

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.504

High

407394

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

413768

RS14A
Small ribosomal subunit protein uS11A

1

5

High-throughput

0.479

High

549530

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

10

High-throughput

0.479

High

558324

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

593727

DBP4
ATP-dependent RNA helicase HCA4

1

16

High-throughput

0.479

High

606782

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.479

High

630292

RRP43
Exosome complex component RRP43

1

2

High-throughput

0.479

High

688493

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

700114

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

8

High-throughput

0.479

High

711091

UTP11
U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.479

High

733617

RL1D1
Ribosome biogenesis protein UTP30

1

7

High-throughput

0.479

High

753199

DBP8
ATP-dependent RNA helicase DBP8

1

15

High-throughput

0.479

High

754225

CIC1
Proteasome-interacting protein CIC1

1

7

High-throughput

0.479

High

755014

RRP4
Exosome complex component RRP4

1

3

High-throughput

0.479

High

755218

LRP1
Exosome complex protein LRP1

1

2

High-throughput

0.479

High

758489

RRP8
25S rRNA

1

4

High-throughput

0.479

High

768133

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

2

High-throughput

0.479

High

774296

RRT14
Regulator of rDNA transcription protein 14

1

2

High-throughput

0.479

High

774764

UTP25
U3 small nucleolar RNA-associated protein 25

1

2

High-throughput

0.479

High

799879

ROK1
ATP-dependent RNA helicase ROK1

1

12

High-throughput

0.479

High

809604

RRP41
Exosome complex component SKI6

1

14

High-throughput

0.479

High

811814

URB2
Nucleolar pre-ribosomal-associated protein 2

1

1

High-throughput

0.479

High

816926

NOL10
Ribosome biogenesis protein ENP2

1

4

High-throughput

0.479

High

816990

MTR3
Exosome complex component MTR3

1

2

High-throughput

0.479

High

860828

RRP46
Exosome complex component RRP46

1

14

High-throughput

0.479

High

861052

UTP8
U3 small nucleolar RNA-associated protein 8

1

2

High-throughput

0.479

High

866637

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

4

High-throughput

0.479

High

975867

TOM1
E3 ubiquitin-protein ligase TOM1

1

15

High-throughput

0.479

High

976892

HAS1
ATP-dependent RNA helicase HAS1

1

20

High-throughput

0.479

High

979420

BUD22
Bud site selection protein 22

1

2

High-throughput

0.479

High

982919

RRP5
rRNA biogenesis protein RRP5

1

9

High-throughput

0.479

High

983784

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

984327

RRP45
Exosome complex component RRP45

1

11

High-throughput

0.479

High

986769

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

3

High-throughput

0.479

High

987109

ESF1
Pre-rRNA-processing protein ESF1

1

2

High-throughput

0.479

High

988489

BFR2
Protein BFR2

1

4

High-throughput

0.479

High

992562

CMS1
Protein CMS1

1

2

High-throughput

0.479

High

993375

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

3

High-throughput

0.479

High

993687

RRP44
Exosome complex exonuclease DIS3

1

4

High-throughput

0.479

High

994587

RRP40
Exosome complex component RRP40

1

2

High-throughput

0.479

High

995875

UTP16
U3 small nucleolar RNA-associated protein 16

1

2

High-throughput

0.479

High

1014905

FCF2
rRNA-processing protein FCF2

1

2

High-throughput

0.479

High

1015082

SAS10
Something about silencing protein 10

1

2

High-throughput

0.479

High

1015243

MAK21
Ribosome biogenesis protein MAK21

1

7

High-throughput

0.479

High

1015331

RRP42
Exosome complex component RRP42

1

11

High-throughput

0.479

High

1015332

NOP56
Nucleolar protein 56

1

11

High-throughput

0.479

High

1015333

RRP36
rRNA biogenesis protein RRP36

1

2

High-throughput

0.479

High

1015335

RRP12
Ribosomal RNA-processing protein 12

1

4

High-throughput

0.479

High

1015336

EFG1P
rRNA-processing protein EFG1

1

2

High-throughput

0.479

High

1015338

NOP14
Nucleolar complex protein 14

1

3

High-throughput

0.479

High

1015339

PNO1
Pre-rRNA-processing protein PNO1

1

2

High-throughput

0.479

High

866198

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

392603

H2A2
Histone H2A.2

1

8

High-throughput

0.437

High

471316

RS22A
Small ribosomal subunit protein uS8A

1

6

High-throughput

0.437

High

633753

PUT3
Proline utilization trans-activator

1

1

High-throughput

0.437

High

663657

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

665109

BMH1
Protein BMH1

1

4

High-throughput

0.437

High

701138

SMY2
Protein SMY2

1

3

High-throughput

0.437

High

762667

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

866556

APJ1
J domain-containing protein APJ1

1

12

High-throughput

0.437

High

977487

BUL2
Ubiquitin ligase-binding protein BUL2

1

1

Small-scale

0.437

High

984225

HRQ1
ATP-dependent helicase HRQ1

1

18

Small-scale

0.437

High

991353

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

995838

SGO1
Shugoshin

1

2

High-throughput

0.437

High

1015337

RS22B
Small ribosomal subunit protein uS8B

1

6

High-throughput

0.437

High

681080

HS104
Heat shock protein 104

1

3

High-throughput

0.407

High

977513

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024