Protein: MLH1
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)

Gene: MLH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: P38920

Gene Ontology (top 5):
GO:0000710 - meiotic mismatch repair
GO:0000713 - meiotic heteroduplex formation
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

536217

PMS1
DNA mismatch repair protein PMS1

29

13

Small-scale

0.993

High

757826

MLH3
DNA mismatch repair protein MLH3

13

13

Small-scale

0.983

High

757823

MLH2
DNA mismatch repair protein MLH2

8

13

Small-scale

0.969

High

639267

MSH2
DNA mismatch repair protein MSH2

7

20

Small-scale

0.963

High

757821

MSH6
DNA mismatch repair protein MSH6

5

20

Small-scale

0.919

High

629333

MSH3
DNA mismatch repair protein MSH3

2

20

Small-scale

0.778

High

757816

MLH1
DNA mismatch repair protein MLH1

2

13

Small-scale

0.778

High

757817

EXO1
Exodeoxyribonuclease 1

10

5

Small-scale

0.755

High

715641

SGS1
ATP-dependent helicase SGS1

5

3

Small-scale

0.704

High

757818

HFM1
ATP-dependent DNA helicase MER3

3

3

Small-scale

0.669

High

757824

NTH2
Endonuclease III homolog 2

3

0

Small-scale

0.654

High

757828

MSH5
MutS protein homolog 5

1

20

Small-scale

0.647

High

550545

PCNA
Proliferating cell nuclear antigen

2

5

Small-scale

0.605

High

493954

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.601

High

491210

HSP71
Heat shock protein SSA1

2

5

Small-scale

0.552

High

757820

ABF2
ARS-binding factor 2, mitochondrial

1

1

High-throughput

0.541

High

632567

RAD51
DNA repair protein RAD51

1

3

High-throughput

0.536

High

743529

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

750705

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.513

High

757830

ISN1
IMP-specific 5'-nucleotidase 1

1

0

High-throughput

0.513

High

397596

OTC
Ornithine carbamoyltransferase

1

1

High-throughput

0.500

High

757825

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

699157

RAD5
DNA repair protein RAD5

1

4

Small-scale

0.481

High

520831

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.479

High

662208

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

693111

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

High-throughput

0.479

High

751307

RFC1
Replication factor C subunit 1

1

6

Small-scale

0.479

High

757822

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

757827

RTK1
Probable serine/threonine-protein kinase RTK1

1

3

High-throughput

0.479

High

407047

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

423961

CBP1
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.458

High

757819

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

757829

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

478188

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

511295

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

754410

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

424517

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

680702

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024