Protein: LSM6
U6 snRNA-associated Sm-like protein LSm6

Gene: LSM6
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: Q06406

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

810539

LSM1
Sm-like protein LSm1

12

20

Small-scale

0.980

High

884830

LSM3
U6 snRNA-associated Sm-like protein LSm3

9

20

Small-scale

0.973

High

767833

LSM4
U6 snRNA-associated Sm-like protein LSm4

7

8

Small-scale

0.972

High

768254

LSM5
U6 snRNA-associated Sm-like protein LSm5

9

6

Small-scale

0.971

High

811668

LSM8
U6 snRNA-associated Sm-like protein LSm8

8

20

Small-scale

0.970

High

635927

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

9

1

Small-scale

0.970

High

746349

LSM2
U6 snRNA-associated Sm-like protein LSm2

6

19

Small-scale

0.945

High

865982

LSM7
U6 snRNA-associated Sm-like protein LSm7

5

20

Small-scale

0.928

High

837115

PRP24
U4/U6 snRNA-associated-splicing factor PRP24

4

2

Small-scale

0.891

High

976048

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

3

High-throughput

0.861

High

704720

PRP8
Pre-mRNA-splicing factor 8

3

2

Small-scale

0.855

High

986596

SMD2
Small nuclear ribonucleoprotein Sm D2

2

6

High-throughput

0.806

High

795424

SMD3
Small nuclear ribonucleoprotein Sm D3

2

19

Small-scale

0.789

High

987143

RU2A
U2 small nuclear ribonucleoprotein A'

2

4

Small-scale

0.754

High

697264

BRR2
Pre-mRNA-splicing helicase BRR2

6

8

Small-scale

0.722

High

731774

SN114
Pre-mRNA-splicing factor SNU114

1

3

High-throughput

0.691

High

605161

XRN1
5'-3' exoribonuclease 1

5

0

High-throughput

0.684

High

762028

DHH1
ATP-dependent RNA helicase DHH1

3

4

High-throughput

0.669

High

830827

PRP31
Pre-mRNA-processing factor 31

3

3

High-throughput

0.667

High

987138

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

3

High-throughput

0.665

High

589098

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

6

High-throughput

0.621

High

766961

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

5

High-throughput

0.618

High

987148

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

3

Small-scale

0.611

High

586443

PRP6
Pre-mRNA-splicing factor 6

1

9

High-throughput

0.536

High

980228

RSE1
Pre-mRNA-splicing factor RSE1

1

2

High-throughput

0.536

High

987141

DIB1
Spliceosomal protein DIB1

1

2

High-throughput

0.536

High

636181

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.518

High

589456

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

6

High-throughput

0.515

High

851995

HFM1
ATP-dependent DNA helicase MER3

1

6

High-throughput

0.508

High

987150

DCP1
mRNA-decapping enzyme subunit 1

1

0

Small-scale

0.493

High

675781

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.479

High

976129

CWC21
Pre-mRNA-splicing factor CWC21

1

1

Small-scale

0.479

High

987147

CLF1
Pre-mRNA-splicing factor CLF1

1

12

Small-scale

0.479

High

663387

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

696893

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

698949

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

735302

RM07
Large ribosomal subunit protein uL5m

1

0

High-throughput

0.458

High

979779

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

987139

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

987146

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

492517

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

495027

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

499085

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

512825

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

692360

PRP19
Pre-mRNA-processing factor 19

1

6

Small-scale

0.445

High

761319

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

960012

SEN1
Helicase SEN1

1

2

Small-scale

0.445

High

700293

RM06
Large ribosomal subunit protein uL6m

1

1

High-throughput

0.437

High

762580

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

404710

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

454471

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

705684

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

644731

YUR1
Probable mannosyltransferase YUR1

1

0

High-throughput

0.265

Low

982848

FMP42
Protein FMP42

1

0

High-throughput

0.265

Low

987144

YL053
Putative uncharacterized protein YLR053C

1

0

High-throughput

0.265

Low

987145

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

516916

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.249

Low

520559

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.249

Low

534505

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.249

Low

544455

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

589404

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

607444

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low

607509

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.249

Low

615631

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.249

Low

629879

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.249

Low

635402

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

635802

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

679587

RM09
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.249

Low

689547

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

710693

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.249

Low

729825

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.249

Low

735176

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.249

Low

735367

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

735419

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

735485

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

735536

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

735579

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

735633

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

735699

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

735783

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

735810

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

743380

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

777376

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.249

Low

852264

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

859772

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

860383

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

864419

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

865651

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

865724

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

866803

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

969386

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

975180

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

985846

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

987140

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low

987142

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

987149

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.249

Low

519997

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

700635

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low

785226

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024