Protein: SMD2
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)

Gene: SMD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: Q06217

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873667

RUXF
Small nuclear ribonucleoprotein F

6

6

High-throughput

0.947

High

986605

RU2A
U2 small nuclear ribonucleoprotein A'

6

4

Small-scale

0.941

High

746348

LSM2
U6 snRNA-associated Sm-like protein LSm2

5

10

Small-scale

0.922

High

766960

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

4

High-throughput

0.892

High

770338

RUXG
Small nuclear ribonucleoprotein G

4

11

High-throughput

0.881

High

986610

RUXE
Small nuclear ribonucleoprotein E

4

1

High-throughput

0.881

High

865981

LSM7
U6 snRNA-associated Sm-like protein LSm7

3

12

High-throughput

0.861

High

767832

LSM4
U6 snRNA-associated Sm-like protein LSm4

3

5

High-throughput

0.858

High

731773

SN114
Pre-mRNA-splicing factor SNU114

3

2

High-throughput

0.855

High

985133

RU1C
U1 small nuclear ribonucleoprotein C

4

0

High-throughput

0.850

High

704719

PRP8
Pre-mRNA-splicing factor 8

3

1

Small-scale

0.839

High

795423

SMD3
Small nuclear ribonucleoprotein Sm D3

3

12

Small-scale

0.839

High

962594

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

3

4

High-throughput

0.839

High

970241

SMD1
Small nuclear ribonucleoprotein Sm D1

3

2

High-throughput

0.839

High

811667

LSM8
U6 snRNA-associated Sm-like protein LSm8

3

12

High-throughput

0.830

High

986602

LUC7
Protein LUC7

3

0

High-throughput

0.811

High

986596

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

6

High-throughput

0.806

High

768253

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

2

High-throughput

0.800

High

976047

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

1

High-throughput

0.789

High

884829

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

14

Small-scale

0.754

High

977078

CEF1
Pre-mRNA-splicing factor CEF1

6

2

Small-scale

0.733

High

697263

BRR2
Pre-mRNA-splicing helicase BRR2

6

6

Small-scale

0.720

High

986604

NCBP2
Nuclear cap-binding protein subunit 2

5

2

High-throughput

0.714

High

960472

NAM8
Protein NAM8

6

0

Small-scale

0.699

High

710223

NCBP1
Nuclear cap-binding protein complex subunit 1

4

2

High-throughput

0.691

High

860157

SNU71
U1 small nuclear ribonucleoprotein component SNU71

4

0

Small-scale

0.664

High

696672

RU1A
U1 small nuclear ribonucleoprotein A

4

0

Small-scale

0.664

High

830826

PRP31
Pre-mRNA-processing factor 31

3

1

High-throughput

0.662

High

692359

PRP19
Pre-mRNA-processing factor 19

3

2

Small-scale

0.650

High

971694

CUS1
Cold sensitive U2 snRNA suppressor 1

3

1

High-throughput

0.650

High

986606

CWC2
Pre-mRNA-splicing factor CWC2

3

1

High-throughput

0.650

High

986614

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.631

High

586528

PRP9
Pre-mRNA-splicing factor PRP9

1

1

High-throughput

0.618

High

986612

PRP46
Pre-mRNA-splicing factor PRP46

2

2

High-throughput

0.611

High

589097

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

3

High-throughput

0.601

High

703274

PRP40
Pre-mRNA-processing protein PRP40

2

1

High-throughput

0.601

High

986600

PRP11
Pre-mRNA-splicing factor PRP11

2

1

High-throughput

0.601

High

986595

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

Small-scale

0.586

High

977612

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

2

0

High-throughput

0.585

High

985856

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.585

High

986609

CLF1
Pre-mRNA-splicing factor CLF1

2

6

Small-scale

0.584

High

986613

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

1

Small-scale

0.584

High

976128

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

859435

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

High-throughput

0.536

High

866833

EFM6
Protein-lysine N-methyltransferase EFM6

1

1

High-throughput

0.515

High

748191

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.513

High

856940

CWC23
Pre-mRNA-splicing factor CWC23

1

0

High-throughput

0.513

High

986597

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

622343

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

3

Small-scale

0.501

High

412879

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.493

High

811086

TAD2
tRNA-specific adenosine deaminase subunit TAD2

1

0

High-throughput

0.493

High

586442

PRP6
Pre-mRNA-splicing factor 6

1

5

High-throughput

0.479

High

589455

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

3

High-throughput

0.479

High

598583

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

2

High-throughput

0.479

High

629397

BUD31
Pre-mRNA-splicing factor BUD31

1

1

High-throughput

0.479

High

638863

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

692432

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.479

High

694251

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.479

High

763250

PRP39
Pre-mRNA-processing factor 39

1

7

High-throughput

0.479

High

778638

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.479

High

836939

SF3B1
U2 snRNP component HSH155

1

2

High-throughput

0.479

High

975836

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

977590

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

9

High-throughput

0.479

High

978479

SYF1
Pre-mRNA-splicing factor SYF1

1

6

High-throughput

0.479

High

980227

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.479

High

986598

DIB1
Spliceosomal protein DIB1

1

1

High-throughput

0.479

High

986599

RDS3
Pre-mRNA-splicing factor RDS3

1

1

High-throughput

0.479

High

986607

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.479

High

986615

HSH49
Protein HSH49

1

1

High-throughput

0.479

High

558265

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

566234

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

598650

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

655755

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.458

High

657770

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

663370

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688434

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

732396

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

733096

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

746603

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.458

High

746880

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

747724

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

748089

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

762576

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

811467

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.458

High

841440

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

861076

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

861580

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

961603

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

972429

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

977574

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

986601

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

986608

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

986611

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

512803

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

743226

CDC27
Anaphase-promoting complex subunit CDC27

1

0

High-throughput

0.426

High

960011

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

754320

FYV4
Small ribosomal subunit protein mS41

1

0

High-throughput

0.282

High

986603

RRG7
Required for respiratory growth protein 7, mitochondrial

1

0

High-throughput

0.269

Low

860380

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024