Protein: FCF1
rRNA-processing protein FCF1 (FAF1-copurifying factor 1)

Gene: FCF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: Q05498

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0004521 - RNA endonuclease activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748699

ENP1
Essential nuclear protein 1

4

1

Small-scale

0.676

High

983786

UTP23
rRNA-processing protein UTP23

1

2

Small-scale

0.647

High

979019

DHR1
Probable ATP-dependent RNA helicase DHR1

3

2

High-throughput

0.640

High

700097

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.618

High

860736

UTP22
U3 small nucleolar RNA-associated protein 22

2

1

High-throughput

0.614

High

811554

MPP10
U3 small nucleolar RNA-associated protein MPP10

2

1

Small-scale

0.601

High

775387

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

634767

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.584

High

635642

PWP2
Periodic tryptophan protein 2

2

1

Small-scale

0.584

High

792578

UTP10
U3 small nucleolar RNA-associated protein 10

2

1

High-throughput

0.584

High

979710

UTP14
U3 small nucleolar RNA-associated protein 14

2

1

High-throughput

0.584

High

983773

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

983789

NOP58
Nucleolar protein 58

2

3

High-throughput

0.584

High

733936

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.576

High

865418

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

798384

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.518

High

593701

DBP4
ATP-dependent RNA helicase HCA4

1

5

High-throughput

0.479

High

630256

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

630535

RRP7
Ribosomal RNA-processing protein 7

1

2

High-throughput

0.479

High

638856

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

733600

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.479

High

758466

RRP8
25S rRNA

1

1

High-throughput

0.479

High

799852

ROK1
ATP-dependent RNA helicase ROK1

1

3

High-throughput

0.479

High

809586

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

810916

MTR4
ATP-dependent RNA helicase DOB1

1

2

High-throughput

0.479

High

860806

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

866612

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

973669

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

975827

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

978628

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.479

High

982868

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.479

High

983766

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

983767

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

983768

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

983772

RRP9
Ribosomal RNA-processing protein 9

1

1

High-throughput

0.479

High

983775

UTP4
U3 small nucleolar RNA-associated protein 4

1

2

High-throughput

0.479

High

983777

RRP44
Exosome complex exonuclease DIS3

1

2

High-throughput

0.479

High

983784

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

983785

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

983787

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

707135

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

711070

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

715981

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

754994

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

755199

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

756783

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

767416

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

768111

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

772673

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

774277

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774747

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

816902

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

816971

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

861023

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

864731

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.458

High

866050

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

970464

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

979235

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

983769

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.458

High

983770

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

983771

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

983774

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

983776

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

983778

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

983779

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

983780

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

983781

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

983782

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

983783

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

983788

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

983790

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

983792

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

983793

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

633569

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.457

High

471256

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

775579

MPH1
ATP-dependent DNA helicase MPH1

1

1

High-throughput

0.437

High

983791

RS22B
Small ribosomal subunit protein uS8B

1

2

High-throughput

0.437

High

424134

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.279

Low

757922

ATC2
Calcium-transporting ATPase 2

1

0

High-throughput

0.279

Low

498595

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.261

Low

554743

HSP26
Heat shock protein 26

1

0

High-throughput

0.261

Low

864435

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.249

Low

478525

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024