Protein: CDK4
Cyclin-dependent kinase 4 (EC 2.7.11.22) (CRK3) (Cell division protein kinase 4) (PSK-J3)

Gene: CDK4
Organism: Mus musculus
Interactions: 27
UniProt ID: P30285

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000785 - chromatin
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629203

CCND1
G1/S-specific cyclin-D1

21

20

Small-scale

0.987

High

673227

CDN1B
Cyclin-dependent kinase inhibitor 1B

6

20

Small-scale

0.928

High

673223

CDN1A
Cyclin-dependent kinase inhibitor 1

4

20

Small-scale

0.873

High

673119

CCND2
G1/S-specific cyclin-D2

3

20

Small-scale

0.805

High

673179

CCND3
G1/S-specific cyclin-D3

3

20

Small-scale

0.805

High

673235

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

17

Small-scale

0.724

High

673229

CEBPA
CCAAT/enhancer-binding protein alpha

3

6

Small-scale

0.680

High

527134

RB
Retinoblastoma-associated protein

3

19

Small-scale

0.655

High

432408

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.647

High

673228

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

15

Small-scale

0.646

High

673230

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

17

Small-scale

0.646

High

673234

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

15

Small-scale

0.646

High

673242

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

6

Small-scale

0.618

High

673232

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

16

High-throughput

0.515

High

550487

H12
Histone H1.2

1

20

Small-scale

0.501

High

673224

PURA
Transcriptional activator protein Pur-alpha

1

2

Small-scale

0.501

High

673225

H11
Histone H1.1

1

20

Small-scale

0.501

High

673226

H15
Histone H1.5

1

20

Small-scale

0.501

High

673240

SET
Protein SET

1

6

Small-scale

0.501

High

572238

PCNA
Proliferating cell nuclear antigen

1

9

Small-scale

0.479

High

673231

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

673233

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

673236

WDTC1
WD and tetratricopeptide repeats protein 1

1

10

High-throughput

0.479

High

673237

CEP57
Centrosomal protein of 57 kDa

1

0

Small-scale

0.458

High

673238

ANM5
Protein arginine N-methyltransferase 5

1

4

Small-scale

0.445

High

673239

MEP50
Methylosome protein WDR77

1

7

Small-scale

0.445

High

673241

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

7

Small-scale

0.445

High


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Last updated: 15 Jul 2024