Protein: RIR1
Ribonucleoside-diphosphate reductase large chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R1 subunit 1) (Ribonucleotide reductase large subunit 1)

Gene: RIR1, RNR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P21524

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

599158

RIR1
Ribonucleoside-diphosphate reductase large chain 1

6

9

Small-scale

0.942

High

456679

RIR2
Ribonucleoside-diphosphate reductase small chain 1

4

13

Small-scale

0.893

High

599159

RIR3
Ribonucleoside-diphosphate reductase large chain 2

4

9

Small-scale

0.890

High

599188

RIR4
Ribonucleoside-diphosphate reductase small chain 2

2

13

Small-scale

0.777

High

599194

SML1
Ribonucleotide reductase inhibitor protein SML1

7

1

Small-scale

0.752

High

543189

HSC82
ATP-dependent molecular chaperone HSC82

3

2

High-throughput

0.633

High

599174

DBP8
ATP-dependent RNA helicase DBP8

2

0

High-throughput

0.602

High

554551

HSP26
Heat shock protein 26

2

2

High-throughput

0.588

High

599185

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

490331

HSP71
Heat shock protein SSA1

2

3

Small-scale

0.576

High

493193

HSP72
Heat shock protein SSA2

2

3

Small-scale

0.576

High

599164

MAS5
Mitochondrial protein import protein MAS5

2

3

Small-scale

0.571

High

599181

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

599169

PP12
Serine/threonine-protein phosphatase PP1-2

1

1

High-throughput

0.536

High

599190

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

599189

ACS2
Acetyl-coenzyme A synthetase 2

1

0

High-throughput

0.513

High

599197

MCA1
Metacaspase-1

1

0

Small-scale

0.513

High

599178

LCF2
Long-chain-fatty-acid--CoA ligase 2

1

1

High-throughput

0.508

High

599165

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.504

High

449907

HSP73
Heat shock protein SSA3

1

3

Small-scale

0.481

High

599160

HSP74
Heat shock protein SSA4

1

3

Small-scale

0.481

High

599202

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.481

High

454177

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.479

High

454551

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.479

High

587927

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.479

High

599161

TRX1
Thioredoxin-1

1

1

High-throughput

0.479

High

599162

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

599166

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

599170

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

599193

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

599201

WTM2
Transcriptional modulator WTM2

1

1

High-throughput

0.479

High

599204

WTM1
Transcriptional modulator WTM1

1

1

High-throughput

0.479

High

599206

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

599172

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

599173

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.458

High

599175

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

599179

AIM2
Protein AIM2

1

0

High-throughput

0.458

High

599187

BPL1
Biotin--protein ligase

1

0

High-throughput

0.458

High

599191

ESP1
Separin

1

0

High-throughput

0.458

High

599192

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

599195

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

599196

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

599198

FOLE
Folylpolyglutamate synthase

1

0

Small-scale

0.458

High

599200

YO283
Broad-specificity phosphatase YOR283W

1

0

High-throughput

0.458

High

599205

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.458

High

599208

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.458

High

599184

BNI1
Protein BNI1

1

1

High-throughput

0.457

High

510251

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

599163

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.445

High

599167

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

599168

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.445

High

599177

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

599203

HSP42
Heat shock protein 42

1

2

High-throughput

0.445

High

599171

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

599180

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

599186

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

599207

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.426

High

599183

JEM1
DnaJ-like chaperone JEM1

1

3

High-throughput

0.407

High

599176

TEM1
Protein TEM1

1

0

High-throughput

0.279

Low

599182

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.261

Low

599199

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024