Protein: ANK2
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)

Gene: ANK2
Organism: Homo sapiens
Interactions: 199
UniProt ID: Q01484

Gene Ontology (top 5):
GO:0002027 - regulation of heart rate
GO:0003283 - atrial septum development
GO:0005200 - structural constituent of cytoskeleton
GO:0005739 - mitochondrion
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

965164

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

12

High-throughput

0.861

High

131995

NCHL1
Neural cell adhesion molecule L1-like protein

2

8

High-throughput

0.811

High

965176

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

3

High-throughput

0.811

High

965172

TNIK
TRAF2 and NCK-interacting protein kinase

2

10

High-throughput

0.762

High

374070

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

3

High-throughput

0.754

High

386546

P53
Cellular tumor antigen p53

1

1

High-throughput

0.724

High

166913

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

13

High-throughput

0.698

High

225134

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

19

High-throughput

0.691

High

118277

HAX1
HCLS1-associated protein X-1

3

0

High-throughput

0.638

High

965113

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.638

High

965162

KTU
Protein kintoun

3

0

High-throughput

0.638

High

965170

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.638

High

891090

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

3

15

Small-scale

0.633

High

965136

RPGF5
Rap guanine nucleotide exchange factor 5

2

3

High-throughput

0.628

High

338292

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.618

High

350083

RASK
GTPase KRas

1

8

High-throughput

0.618

High

433701

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.618

High

507954

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.618

High

513849

DMD
Dystrophin

1

19

Small-scale

0.618

High

557660

NCK1
SH2/SH3 adapter protein NCK1

1

3

High-throughput

0.618

High

665581

EPHB2
Ephrin type-B receptor 2

1

5

High-throughput

0.618

High

924484

GRB2
Growth factor receptor-bound protein 2

1

7

High-throughput

0.618

High

965107

ZYX
Zyxin

1

6

High-throughput

0.618

High

965118

OBSCN
Obscurin

1

7

Small-scale

0.618

High

965126

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

965168

RRBP1
Ribosome-binding protein 1

2

10

High-throughput

0.588

High

965159

POPD2
Popeye domain-containing protein 2

2

0

High-throughput

0.585

High

965150

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

15

Small-scale

0.585

High

717002

CTNB1
Catenin beta-1

2

4

Small-scale

0.584

High

965147

NDEL1
Nuclear distribution protein nudE-like 1

2

8

High-throughput

0.576

High

713

KV240
Immunoglobulin kappa variable 2-40

1

1

High-throughput

0.575

High

164604

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

20

High-throughput

0.575

High

349253

RASH
GTPase HRas

1

6

High-throughput

0.575

High

353210

LV208
Immunoglobulin lambda variable 2-8

1

1

High-throughput

0.575

High

353770

IGHG2
Immunoglobulin heavy constant gamma 2

1

4

High-throughput

0.575

High

428145

TBB5
Tubulin beta chain

1

2

High-throughput

0.575

High

484108

CALM3
Calmodulin-3

1

1

High-throughput

0.575

High

685308

L1CAM
Neural cell adhesion molecule L1

1

8

High-throughput

0.575

High

862028

DAPK1
Death-associated protein kinase 1

1

17

High-throughput

0.575

High

925204

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.575

High

963292

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.575

High

965100

LSAMP
Limbic system-associated membrane protein

1

2

High-throughput

0.575

High

965102

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

19

High-throughput

0.575

High

965103

TBB2A
Tubulin beta-2A chain

1

2

High-throughput

0.575

High

965128

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.575

High

965174

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

20

High-throughput

0.575

High

965105

KCJ11
ATP-sensitive inward rectifier potassium channel 11

1

2

Small-scale

0.569

High

965154

Q9H4D1
Protein kinase

1

15

High-throughput

0.555

High

496871

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.554

High

917128

H4
Histone H4

1

1

High-throughput

0.553

High

965177

PLAK2
PALM2-AKAP2 fusion protein

2

3

High-throughput

0.552

High

306116

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

15

Small-scale

0.550

High

965153

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

15

Small-scale

0.550

High

857104

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.546

High

279290

DNJB5
DnaJ homolog subfamily B member 5

1

3

High-throughput

0.541

High

965109

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.537

High

297337

MYO1D
Unconventional myosin-Id

1

7

High-throughput

0.536

High

590852

BTF3
Transcription factor BTF3

1

1

High-throughput

0.536

High

943195

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.536

High

965179

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

10

High-throughput

0.536

High

883487

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

18

High-throughput

0.528

High

82403

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

2

High-throughput

0.514

High

965160

TANC2
Protein TANC2

1

13

High-throughput

0.514

High

117388

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.513

High

849531

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

965134

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

965166

EHD3
EH domain-containing protein 3

1

12

Small-scale

0.506

High

560361

EPB42
Protein 4.2

1

1

Small-scale

0.501

High

689704

NAC1
Sodium/calcium exchanger 1

1

1

Small-scale

0.501

High

787897

EPS15
Epidermal growth factor receptor substrate 15

1

12

High-throughput

0.501

High

965144

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

15

Small-scale

0.501

High

965148

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

15

Small-scale

0.501

High

965099

ABCC8
ATP-binding cassette sub-family C member 8

1

1

Small-scale

0.500

High

965104

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.500

High

965131

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

3

High-throughput

0.489

High

965133

CE120
Centrosomal protein of 120 kDa

1

9

High-throughput

0.488

High

965119

ECM29
Proteasome adapter and scaffold protein ECM29

1

3

Small-scale

0.481

High

279514

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

308623

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

384666

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

430141

PROF1
Profilin-1

1

3

High-throughput

0.479

High

547010

EZRI
Ezrin

1

10

High-throughput

0.479

High

636308

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.479

High

669988

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

779260

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

897704

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

944743

RED1
Double-stranded RNA-specific editase 1

1

5

High-throughput

0.479

High

965110

OCLN
Occludin

1

2

High-throughput

0.479

High

965130

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

965135

OTU7A
OTU domain-containing protein 7A

1

9

High-throughput

0.479

High

965151

EHD4
EH domain-containing protein 4

1

11

Small-scale

0.479

High

965155

EHD1
EH domain-containing protein 1

1

12

Small-scale

0.479

High

965167

EHD2
EH domain-containing protein 2

1

12

Small-scale

0.479

High

965169

DNJB4
DnaJ homolog subfamily B member 4

1

3

High-throughput

0.479

High

965173

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.479

High

888021

SC61G
Protein transport protein Sec61 subunit gamma

1

0

High-throughput

0.458

High

965141

MTEF1
Transcription termination factor 1, mitochondrial

1

0

High-throughput

0.458

High

965142

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

Small-scale

0.458

High

965171

DCTN4
Dynactin subunit 4

1

0

Small-scale

0.458

High

965101

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

High-throughput

0.457

High

212310

CYH3
Cytohesin-3

1

3

High-throughput

0.445

High

214553

MYO1B
Unconventional myosin-Ib

1

8

High-throughput

0.445

High

235805

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.445

High

239946

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

264294

GGYF1
GRB10-interacting GYF protein 1

1

7

High-throughput

0.445

High

417237

ENOA
Alpha-enolase

1

3

High-throughput

0.445

High

418181

NPM
Nucleophosmin

1

1

High-throughput

0.445

High

422166

NFL
Neurofilament light polypeptide

1

15

High-throughput

0.445

High

422380

NFM
Neurofilament medium polypeptide

1

15

High-throughput

0.445

High

438082

HS90B
Heat shock protein HSP 90-beta

1

7

High-throughput

0.445

High

443464

VIME
Vimentin

1

15

High-throughput

0.445

High

451004

GNAO

1

2

High-throughput

0.445

High

483759

HS71A
Heat shock 70 kDa protein 1A

1

6

High-throughput

0.445

High

501987

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.445

High

503916

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.445

High

542282

PLAK
Junction plakoglobin

1

5

High-throughput

0.445

High

547329

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.445

High

582232

NUCL
Nucleolin

1

2

High-throughput

0.445

High

599563

SYT1
Synaptotagmin-1

1

1

High-throughput

0.445

High

640716

CTNA2
Catenin alpha-2

1

2

High-throughput

0.445

High

646808

1433T
14-3-3 protein theta

1

13

High-throughput

0.445

High

669687

RABP1
Cellular retinoic acid-binding protein 1

1

2

High-throughput

0.445

High

724782

MYH9
Myosin-9

1

4

High-throughput

0.445

High

725139

MYH10
Myosin-10

1

3

High-throughput

0.445

High

725949

ADDA
Alpha-adducin

1

3

High-throughput

0.445

High

729068

K22E
Keratin, type II cytoskeletal 2 epidermal

1

11

High-throughput

0.445

High

781878

PERI
Peripherin

1

15

High-throughput

0.445

High

799969

VDAC2
Voltage-dependent anion-selective channel protein 2

1

1

High-throughput

0.445

High

807690

MAP1B
Microtubule-associated protein 1B

1

11

High-throughput

0.445

High

837605

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

2

High-throughput

0.445

High

886375

RTP1
Receptor-transporting protein 1

1

1

High-throughput

0.445

High

891699

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.445

High

905838

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.445

High

909455

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

920939

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

3

High-throughput

0.445

High

923644

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.445

High

926936

1433Z
14-3-3 protein zeta/delta

1

13

High-throughput

0.445

High

930079

ACTH
Actin, gamma-enteric smooth muscle

1

6

High-throughput

0.445

High

946226

BASP1
Brain acid soluble protein 1

1

4

High-throughput

0.445

High

965098

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.445

High

965108

AINX
Alpha-internexin

1

12

High-throughput

0.445

High

965111

DREB
Drebrin

1

6

High-throughput

0.445

High

965115

ACTBL
Beta-actin-like protein 2

1

6

High-throughput

0.445

High

965116

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

3

High-throughput

0.445

High

965120

VIR
Protein virilizer homolog

1

3

High-throughput

0.445

High

965125

MPRIP
Myosin phosphatase Rho-interacting protein

1

14

High-throughput

0.445

High

965139

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

3

High-throughput

0.445

High

965140

FMNL2
Formin-like protein 2

1

2

High-throughput

0.445

High

965146

SRCN1
SRC kinase signaling inhibitor 1

1

4

High-throughput

0.445

High

965152

PABP3
Polyadenylate-binding protein 3

1

2

High-throughput

0.445

High

965156

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

4

High-throughput

0.445

High

965158

PKHA5
Pleckstrin homology domain-containing family A member 5

1

13

High-throughput

0.445

High

965165

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

3

High-throughput

0.445

High

965178

E41L3
Band 4.1-like protein 3

1

12

High-throughput

0.445

High

965180

MYO5A
Unconventional myosin-Va

1

3

High-throughput

0.445

High

965181

SNX9
Sorting nexin-9

1

6

High-throughput

0.445

High

934668

H31
Histone H3.1

1

2

High-throughput

0.437

High

965127

H32
Histone H3.2

1

2

High-throughput

0.437

High

344661

CO3
Complement C3

1

0

High-throughput

0.426

High

358497

CO1A1
Collagen alpha-1(I) chain

1

0

High-throughput

0.426

High

378028

PRIO
Major prion protein

1

0

High-throughput

0.426

High

570254

NEUM
Neuromodulin

1

0

High-throughput

0.426

High

575017

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.426

High

735924

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.426

High

825168

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.426

High

842459

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.426

High

869941

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.426

High

887101

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

0

High-throughput

0.426

High

899716

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.426

High

922526

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.426

High

932659

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.426

High

965094

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.426

High

965095

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.426

High

965096

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.426

High

965097

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.426

High

965112

FSCN1
Fascin

1

0

High-throughput

0.426

High

965114

RABL6
Rab-like protein 6

1

0

High-throughput

0.426

High

965121

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.426

High

965122

CDC73
Parafibromin

1

0

High-throughput

0.426

High

965129

R4RL2
Reticulon-4 receptor-like 2

1

0

High-throughput

0.426

High

965137

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.426

High

965157

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

268682

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.407

High

722218

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.407

High

852879

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

3

High-throughput

0.407

High

965106

NONO
Non-POU domain-containing octamer-binding protein

1

3

High-throughput

0.407

High

965132

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.407

High

965138

MAP6
Microtubule-associated protein 6

1

10

High-throughput

0.407

High

965143

PSD2
PH and SEC7 domain-containing protein 2

1

4

High-throughput

0.407

High

965175

COR2B
Coronin-2B

1

3

High-throughput

0.407

High

965145

CRNL1
Crooked neck-like protein 1

1

0

High-throughput

0.279

Low

965149

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

559657

H12
Histone H1.2

1

0

High-throughput

0.269

Low

100687

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

965163

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

965117

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.232

Low

965123

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.232

Low

965124

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.232

Low

965161

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024