HitPredict
Protein: METF
5,10-methylenetetrahydrofolate reductase (MTHFR) (EC 1.5.1.54) (NADH-dependent 5,10-methylenetetrahydrofolate reductase)

Gene: METF
Organism: Escherichia coli K-12
Interactions: 4
UniProt ID: P0AEZ1

Gene Ontology (top 5):
GO:0004489 - methylenetetrahydrofolate reductase [NAD(P)H] activity
GO:0005829 - cytosol
GO:0009086 - methionine biosynthetic process
GO:0032991 - protein-containing complex
GO:0035999 - tetrahydrofolate interconversion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

489619

 CH60
Chaperonin GroEL

2

1

Small-scale

 0.611

High

500533

 DNLJ
DNA ligase

1

0

High-throughput

 0.513

High

500534

 MLIC
Membrane-bound lysozyme inhibitor of C-type lysozyme

1

0

High-throughput

 0.279

Low

500535

 AAEB
p-hydroxybenzoic acid efflux pump subunit AaeB

1

0

High-throughput

 0.279

Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025