HitPredict - High confidence protein-protein interactions

Protein: THIC
Phosphomethylpyrimidine synthase (EC 4.1.99.17) (Hydroxymethylpyrimidine phosphate synthase) (HMP-P synthase) (HMP-phosphate synthase) (HMPP synthase) (Thiamine biosynthesis protein ThiC)

Gene: THIC
Organism: Escherichia coli K-12
Interactions: 8
UniProt ID: P30136

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0009228 - thiamine biosynthetic process
GO:0009229 - thiamine diphosphate biosynthetic process
GO:0016830 - carbon-carbon lyase activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Category	Interaction Score	Confidence
497891	NAPG Ferredoxin-type protein NapG	1	High-throughput	0.513	High
596592	HYCF Formate hydrogenlyase subunit 6	1	High-throughput	0.513	High
717672	RNB Exoribonuclease 2	1	High-throughput	0.513	High
491790	MOAC Cyclic pyranopterin monophosphate synthase	1	High-throughput	0.279	Low
498463	NAPC Cytochrome c-type protein NapC	1	High-throughput	0.279	Low
498985	HEMG Protoporphyrinogen IX dehydrogenase [quinone]	1	High-throughput	0.279	Low
559624	GLPD Aerobic glycerol-3-phosphate dehydrogenase	1	High-throughput	0.279	Low
717673	YNCE Uncharacterized protein YncE	1	High-throughput	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025