HitPredict

Protein: R1A
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 (Leader protein) (Non-structural protein 1) (nsp1); Non-structural protein 2 (nsp2) (p65 homolog); Papain-like protease nsp3 (PL-PRO) (EC 3.4.19.12) (EC 3.4.22.-) (Non-structural protein 3) (nsp3) (PL2-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase nsp5 (3CL-PRO) (3CLp) (EC 3.4.22.69) (Main protease) (Mpro) (Non-structural protein 5) (nsp5) (SARS coronavirus main proteinase); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); RNA-capping enzyme subunit nsp9 (Non-structural protein 9) (nsp9) (EC 2.7.7.50); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]

Gene: R1A, 1a
Organism: Severe acute respiratory syndrome-related coronavirus
Interactions: 4
UniProt ID: P0C6U8

Gene Ontology (top 5):
GO:0002151 - G-quadruplex RNA binding
GO:0003727 - single-stranded RNA binding
GO:0003968 - RNA-dependent RNA polymerase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0004519 - endonuclease activity