Protein: SMD3
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)

Gene: SMD3
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P43321

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

766915

RSMB
Small nuclear ribonucleoprotein-associated protein B

8

15

Small-scale

0.964

High

704680

PRP8
Pre-mRNA-splicing factor 8

6

7

Small-scale

0.943

High

795410

SMD1
Small nuclear ribonucleoprotein Sm D1

5

7

Small-scale

0.922

High

770312

RUXG
Small nuclear ribonucleoprotein G

5

20

Small-scale

0.912

High

795393

LSM8
U6 snRNA-associated Sm-like protein LSm8

5

20

Small-scale

0.912

High

795402

RUXF
Small nuclear ribonucleoprotein F

5

19

Small-scale

0.912

High

795428

LUC7
Protein LUC7

4

2

High-throughput

0.896

High

795430

RU2A
U2 small nuclear ribonucleoprotein A'

4

12

Small-scale

0.886

High

795412

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

7

Small-scale

0.847

High

731734

SN114
Pre-mRNA-splicing factor SNU114

3

11

Small-scale

0.839

High

795423

SMD2
Small nuclear ribonucleoprotein Sm D2

3

12

Small-scale

0.839

High

795435

RUXE
Small nuclear ribonucleoprotein E

3

14

Small-scale

0.839

High

795421

RU1C
U1 small nuclear ribonucleoprotein C

4

0

Small-scale

0.836

High

767788

LSM4
U6 snRNA-associated Sm-like protein LSm4

2

15

Small-scale

0.789

High

795424

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

19

Small-scale

0.789

High

586498

PRP9
Pre-mRNA-splicing factor PRP9

2

4

High-throughput

0.776

High

746305

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

16

Small-scale

0.754

High

795407

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

2

14

High-throughput

0.754

High

697223

BRR2
Pre-mRNA-splicing helicase BRR2

7

20

Small-scale

0.742

High

795403

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

20

High-throughput

0.737

High

795411

CUS1
Cold sensitive U2 snRNA suppressor 1

5

4

High-throughput

0.714

High

795414

CEF1
Pre-mRNA-splicing factor CEF1

5

8

Small-scale

0.712

High

795405

NAM8
Protein NAM8

5

2

Small-scale

0.712

High

710182

NCBP1
Nuclear cap-binding protein complex subunit 1

4

1

High-throughput

0.691

High

795431

CWC2
Pre-mRNA-splicing factor CWC2

3

6

High-throughput

0.667

High

696642

RU1A
U1 small nuclear ribonucleoprotein A

4

0

Small-scale

0.664

High

703233

PRP40
Pre-mRNA-processing protein PRP40

3

6

High-throughput

0.662

High

586416

PRP6
Pre-mRNA-splicing factor 6

3

15

Small-scale

0.650

High

692309

PRP19
Pre-mRNA-processing factor 19

3

17

Small-scale

0.650

High

795395

PRP31
Pre-mRNA-processing factor 31

3

8

Small-scale

0.650

High

795438

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

3

4

Small-scale

0.650

High

694088

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

3

8

High-throughput

0.643

High

795429

NCBP2
Nuclear cap-binding protein subunit 2

3

3

High-throughput

0.640

High

795398

SNU71
U1 small nuclear ribonucleoprotein component SNU71

3

0

Small-scale

0.634

High

795417

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

3

0

High-throughput

0.634

High

795422

SN309
Pre-mRNA-splicing factor SNT309

3

0

High-throughput

0.634

High

763234

PRP39
Pre-mRNA-processing factor 39

2

20

High-throughput

0.601

High

795418

SYF1
Pre-mRNA-splicing factor SYF1

2

20

High-throughput

0.601

High

795420

RSE1
Pre-mRNA-splicing factor RSE1

2

3

High-throughput

0.601

High

795427

PRP11
Pre-mRNA-splicing factor PRP11

2

5

High-throughput

0.601

High

589082

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

17

Small-scale

0.584

High

795406

PRP38
Pre-mRNA-splicing factor 38

2

1

Small-scale

0.584

High

795426

DIB1
Spliceosomal protein DIB1

2

4

Small-scale

0.584

High

795434

CLF1
Pre-mRNA-splicing factor CLF1

2

20

Small-scale

0.584

High

795436

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

1

Small-scale

0.584

High

657742

YJU2
Splicing factor YJU2

2

0

High-throughput

0.576

High

705318

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.571

High

795413

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

795397

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

High-throughput

0.536

High

795425

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.513

High

678746

RAD16
DNA repair protein RAD16

1

4

High-throughput

0.508

High

752417

STB5
Protein STB5

1

1

High-throughput

0.508

High

795404

SEN1
Helicase SEN1

1

5

High-throughput

0.508

High

622320

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

6

Small-scale

0.501

High

795394

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.493

High

614511

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

High-throughput

0.486

High

690542

CDC12
Cell division control protein 12

1

0

High-throughput

0.486

High

795409

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

0

High-throughput

0.486

High

558113

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

Small-scale

0.479

High

598631

ISY1
Pre-mRNA-splicing factor ISY1

1

2

High-throughput

0.479

High

629379

BUD31
Pre-mRNA-splicing factor BUD31

1

1

High-throughput

0.479

High

655720

PRP45
Pre-mRNA-processing protein 45

1

4

High-throughput

0.479

High

662539

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

692021

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

3

High-throughput

0.479

High

692406

PRP21
Pre-mRNA-splicing factor PRP21

1

6

High-throughput

0.479

High

746861

SLT11
Pre-mRNA-splicing factor SLT11

1

2

High-throughput

0.479

High

762311

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

778619

PRP17
Pre-mRNA-processing factor 17

1

18

High-throughput

0.479

High

795396

SF3B1
U2 snRNP component HSH155

1

7

High-throughput

0.479

High

795399

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.479

High

795416

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

20

High-throughput

0.479

High

795437

PRP46
Pre-mRNA-splicing factor PRP46

1

15

High-throughput

0.479

High

613067

SPA2
Protein SPA2

1

1

High-throughput

0.464

High

566190

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

733071

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

747712

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

748072

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

795400

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

795401

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

795415

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

795432

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

491577

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

494250

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

511727

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

694924

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

761249

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

768722

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

760636

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

772559

JEM1
DnaJ-like chaperone JEM1

1

2

High-throughput

0.407

High

795408

ARG56
Protein ARG5,6, mitochondrial [Cleaved into: N-acetyl-gamma-glutamyl-phosphate reductase

1

0

High-throughput

0.269

Low

795433

YOR97
Uncharacterized protein YOR097C

1

0

High-throughput

0.269

Low

757888

REV7
DNA polymerase zeta processivity subunit

1

0

High-throughput

0.265

Low

795419

VBA1
Vacuolar basic amino acid transporter 1

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024