HitPredict
Protein: THI11
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11 (HMP-P synthase) (Hydroxymethylpyrimidine phosphate synthase) (EC 2.-.-.-) (Thiamine biosynthesis protein 11) (Thiamine pyrimidine synthase)

Gene: THI11
Organism: Saccharomyces cerevisiae S288C
Interactions: 10
UniProt ID: P47183

Gene Ontology (top 5):
GO:0009228 - thiamine biosynthetic process
GO:0009229 - thiamine diphosphate biosynthetic process
GO:0046872 - metal ion binding
GO:0106344 - 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

866311

 SNZ2
Probable pyridoxal 5'-phosphate synthase subunit SNZ2

1

0

Small-scale

 0.438

High

524460

 HSP71
Heat shock protein SSA1

1

1

High-throughput

 0.407

High

527090

 HSP72
Heat shock protein SSA2

1

1

High-throughput

 0.407

High

741920

 HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

 0.407

High

742893

 HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

 0.407

High

866310

 PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

 0.269

Low

866313

 ATG17
Autophagy-related protein 17

1

0

High-throughput

 0.269

Low

866312

 NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

 0.238

Low

545457

 SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

 0.232

Low

863638

 PFD1
Prefoldin subunit 1

1

0

High-throughput

 0.232

Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025