HitPredict
Protein: PDE8
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 (EC 3.1.4.53) (Phosphodiesterase 8)

Gene: PDE8
Organism: Drosophila melanogaster
Interactions: 8
UniProt ID: Q6NNF2

Gene Ontology (top 5):
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0006198 - cAMP catabolic process
GO:0007498 - mesoderm development
GO:0019933 - cAMP-mediated signaling
GO:0046058 - cAMP metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

963911

 TBB2
Tubulin beta-2 chain

1

0

High-throughput

 0.458

High

1236808

 EXOC2
Exocyst complex component 2

1

1

High-throughput

 0.439

High

1236803

 Q7KTJ7
Basigin, isoform G

1

1

High-throughput

 0.437

High

1236807

 Q9VBT4
IP12282p

2

0

High-throughput

 0.310

High

1236804

 Q95TZ0
phosphoribosylaminoimidazolesuccinocarboxamide synthase

1

0

High-throughput

 0.232

Low

1236805

 Q961H6
GH23019p

1

0

High-throughput

 0.232

Low

1236806

 Q961J8
GH20109p

1

0

High-throughput

 0.232

Low

1236809

 Q9W0D9
choline-phosphate cytidylyltransferase

1

0

High-throughput

 0.232

Low

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Last updated: 11Aug2025