HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: DLGP3 (Q6PFD5)
Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3)
Gene: Dlgap3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	27507650, 28706196, 28671696, 36417873
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0045202 - synapse GO:0050804 - modulation of chemical synaptic transmission GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 977
+	Mm
		69799 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		B1AS06_MOUSE (1-977): 0: 1220: 98.87
+	Mm
		100038 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		DLGP2_MOUSE (1-977): 0: 1084: 45.30
+	Mm
		100084 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		DLGP1_MOUSE (1-977): 0: 1047: 37.73
+	Mm
		69910 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		DLGP4_MOUSE (1-977): 0: 949: 35.66
+	Mm
		1012209 Q0VAV5_MOUSE (17-1338): 0: 890: 43.23		DLGP1_MOUSE (1-977): 0: 1047: 37.73
+	Mm
		93234 E9PW37_MOUSE (17-1338): 0: 887: 43.30		DLGP1_MOUSE (1-977): 0: 1047: 37.73
+	Mm
		1112550 DAB2P_MOUSE (97-1339): 0: 850: 47.79		DLGP1_MOUSE (1-977): 0: 1047: 37.73
+	Mm
		99977 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		Q3UVU8_MOUSE (367-908): 0: 650: 38.07
+	Mm
		1113183 IQGA2_MOUSE (216-731): 3.33e-115: 398: 14.09		DLGP1_MOUSE (1-977): 0: 1047: 37.73