HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: ANS1B (Q8BIZ1)
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1)
Gene: Anks1b

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	27507650, 28706196, 28671696, 36417873, 31388001
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0098978 - glutamatergic synapse GO:0099092 - postsynaptic density, intracellular component
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 1259
+	Hs
		1139204 DAB2P_HUMAN (97-1339): 0: 859: 47.63		ANS1B_HUMAN (1-1236): 0: 863: 92.86
+	Hs
		1191813 NGAP_HUMAN (84-1338): 0: 800: 43.48		ANS1B_HUMAN (1-1236): 0: 863: 92.86
+	Hs
		1268491 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANS1A_HUMAN (1-980): 4.87e-69: 255: 29.07
+	Hs
		1299786 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		KDIS_HUMAN (33-390): 1.49e-65: 246: 19.18
+	Hs
		556720 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANK1_HUMAN (48-997): 3.96e-55: 213: 11.94
+	Hs
		1164363 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		POTEE_HUMAN (3-397): 9.83e-42: 169: 20.55
+	Hs
		60399 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		POTEF_HUMAN (3-397): 1.81e-41: 168: 20.55
+	Mm
		56839 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		TANC2_MOUSE (104-1050): 2.06e-29: 129: 11.75
+	Hs
		1299752 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41
+	Hs
		1115792 DAB2P_HUMAN (97-1339): 0: 859: 47.63		Q49AR9_HUMAN (798-1254): 4.29e-96: 321: 53.64
+	Mm
		100050 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		ANK2_MOUSE (66-258): 3.34e-10: 67: 30.05
+	Hs
		965139 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANK2_HUMAN (66-258): 2.94e-10: 67.4: 30.05
+	Hs
		1139206 DAB2P_HUMAN (97-1339): 0: 859: 47.63		ANS1A_HUMAN (1-980): 4.87e-69: 255: 29.07
+	Hs
		1021395 IQGA2_HUMAN (216-691): 7.87e-116: 400: 13.38		ANK3_HUMAN (5-322): 1.58e-61: 234: 21.75
+	Hs
		1201452 IQGA3_HUMAN (214-734): 8.69e-110: 383: 13.64		Q9H4D1_HUMAN (4-138): 1.62e-27: 122: 23.29
+	Hs
		883552 IQGA3_HUMAN (214-734): 8.69e-110: 383: 13.64		RIPK4_HUMAN (4-138): 1.7e-27: 122: 23.29
+	Hs
		598527 NF1_HUMAN (408-712): 2.96e-82: 301: 23.21		TANC2_HUMAN (104-1028): 3.1e-30: 132: 12.41