HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: ANK2 (Q8C8R3)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin)
Gene: ANK2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27507650, 28706196, 28671696, 36417873
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0019901 - protein kinase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 3898
+	Hs
		965139 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANK2_HUMAN (1-3898): 0: 1678: 80.49
+	Hs
		556720 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ANK1_HUMAN (2-747): 0: 761: 33.73
+	Hs
		1021395 IQGA2_HUMAN (216-691): 7.87e-116: 400: 13.38		ANK3_HUMAN (1021-1261): 3.23e-10: 69.2: 12.10