HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: IQEC1 (Q8R0S2)
IQ motif and SEC7 domain-containing protein 1
Gene: Iqsec1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27507650, 28706196, 28671696, 36417873
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0098978 - glutamatergic synapse GO:0099092 - postsynaptic density, intracellular component
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 961
+	Hs
		1150546 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		IQEC1_HUMAN (1-961): 0: 1169: 95.64
+	Mm
		99982 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		IQEC2_MOUSE (19-956): 0: 861: 58.81
+	Mm
		60019 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		A4GZ26_MOUSE (22-956): 0: 830: 57.96
+	Mm
		99947 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		CYH2_MOUSE (465-828): 7.11e-102: 325: 27.40
+	Hs
		1299724 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		CYH2_HUMAN (465-828): 1.76e-102: 327: 27.67
+	Hs
		1061941 GAPD1_HUMAN (412-1068): 2.04e-130: 439: 13.36		GBF1_HUMAN (324-722): 6.8e-91: 320: 22.69