HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: SGIP1 (Q8VD37)
SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein)
Gene: SGIP1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0017124 - SH3 domain binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 806
+	Hs
		262308 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ULK1_HUMAN (141-522): 1.8e-49: 190: 19.72
+	Mm
		99892 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		ULK1_MOUSE (150-522): 3.29e-34: 143: 17.79
+	Mm
		88450 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		D3Z656_MOUSE (247-694): 8.06e-19: 94.1: 11.58
+	Mm
		99981 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Mm
		100055 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		SYNJ1_MOUSE (320-732): 4.38e-12: 72.2: 13.64
+	Hs
		203258 NGAP_HUMAN (84-1338): 0: 800: 43.48		SYNJ1_HUMAN (288-649): 3.6e-11: 69.4: 12.43
+	Hs
		596434 RASA1_HUMAN (184-715): 9.24e-130: 428: 23.82		MAGE1_HUMAN (125-445): 7.2e-10: 64.7: 15.69
+	Mm
		980215 NF1_MOUSE (408-712): 3.83e-82: 300: 23.51		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70