HitPredict

Interactor 1: Q0E8K8 (Q0E8K8)
FI21816p1 (FI22362p1) (Vitamin D[[3]] up-regulated protein 1, isoform A) (Vitamin D[[3]] up-regulated protein 1, isoform B) (Vitamin D[[3]] up-regulated protein 1, isoform C) (Vitamin D[[3]] up-regulated protein 1, isoform D) (Vitamin D[[3]] up-regulated protein 1, isoform E)
Gene: Vdup1

Interactor 2: Q9VXR3 (Q9VXR3)
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)
Gene: HUWE1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	38270169
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Dm			1 5146
+	Hs
		1252814 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		WWP1_HUMAN (4308-5144): 0: 737: 25.03
+	Hs
		1252807 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		ITCH_HUMAN (4383-5144): 0: 701: 24.81
+	Hs
		125595 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		WWP2_HUMAN (4252-5144): 0: 694: 23.03
+	Dm
		115611 Q8SYU5_DROME (6-342): 2.49e-98: 300: 21.97		M9PFK2_DROME (4284-5143): 0: 676: 23.33
+	Dm
		115614 Q9VI00_DROME (6-341): 8.93e-99: 300: 22.22		M9PFK2_DROME (4284-5143): 0: 676: 23.33
+	Dm
		1249345 Q8SYU5_DROME (6-342): 2.49e-98: 300: 21.97		NEDD4_DROME (4290-5143): 0: 676: 23.51
+	Dm
		1367624 Q9VI00_DROME (6-341): 8.93e-99: 300: 22.22		NEDD4_DROME (4290-5143): 0: 676: 23.51
+	Hs
		1252808 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		NED4L_HUMAN (4371-5144): 0: 683: 26.12
+	Dm
		1367634 Q9VI00_DROME (6-341): 8.93e-99: 300: 22.22		SUDX_DROME (4527-5143): 0: 650: 29.79
+	Ce
		1341514 Q9XXI4_CAEEL (10-340): 5.2e-99: 300: 21.17		WWP1_CAEEL (4544-5144): 0: 649: 30.53
+	Hs
		1252817 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		HECW2_HUMAN (3925-5145): 0: 619: 18.59
+	Dm
		1249317 Q8SYU5_DROME (6-342): 2.49e-98: 300: 21.97		SMUF1_DROME (4207-5143): 2.92e-177: 580: 23.43
+	Dm
		1337204 Q9I7L0_DROME (6-341): 1.93e-103: 312: 19.94		Q9W325_DROME (4719-5144): 8.17e-176: 550: 34.27
+	Dm
		89897 Q9I7L0_DROME (6-341): 1.93e-103: 312: 19.94		D5SHR3_DROME (4727-5144): 4.53e-175: 548: 34.92
+	Dm
		1249359 Q8SYU5_DROME (6-342): 2.49e-98: 300: 21.97		Q9W325_DROME (4719-5144): 8.17e-176: 550: 34.27
+	Dm
		1367630 Q9VI00_DROME (6-341): 8.93e-99: 300: 22.22		Q9W325_DROME (4719-5144): 8.17e-176: 550: 34.27
+	Dm
		89895 Q8SYU5_DROME (6-342): 2.49e-98: 300: 21.97		D5SHR3_DROME (4727-5144): 4.53e-175: 548: 34.92
+	Dm
		89904 Q9VI00_DROME (6-341): 8.93e-99: 300: 22.22		D5SHR3_DROME (4727-5144): 4.53e-175: 548: 34.92
+	Dm
		89903 Q9VHZ7_DROME (6-306): 2.26e-91: 283: 23.15		D5SHR3_DROME (4727-5144): 4.53e-175: 548: 34.92
+	Hs
		1192131 ARRD2_HUMAN (1-334): 2.47e-93: 285: 24.44		HUWE1_HUMAN (3086-3641): 3.4e-09: 66.2: 12.33