HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: DREB (Q9QXS6)
Drebrin (Developmentally-regulated brain protein)
Gene: Dbn1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0016020 - membrane GO:0043198 - dendritic shaft GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 706
+	Hs
		1085033 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		DREB_HUMAN (1-706): 1.28e-81: 274: 80.03
+	Mm
		99996 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		DBNL_MOUSE (3-398): 2.02e-59: 208: 31.31
+	Mm
		99958 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		TNIK_MOUSE (188-570): 1.93e-37: 152: 13.85
+	Hs
		1299784 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		TNIK_HUMAN (187-531): 8.58e-39: 156: 16.10
+	Mm
		100055 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		SYNJ1_MOUSE (118-661): 2.65e-09: 62.9: 9.93
+	Mm
		88450 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		D3Z656_MOUSE (113-586): 9.14e-09: 61: 10.73
+	Hs
		1336728 NGAP_HUMAN (84-1338): 0: 800: 43.48		MYO10_HUMAN (139-421): 3.12e-26: 117: 18.93
+	Hs
		596408 RASA1_HUMAN (184-715): 9.24e-130: 428: 23.82		DREB_HUMAN (1-706): 1.28e-81: 274: 80.03
+	Hs
		809318 IQGA1_HUMAN (219-723): 6.44e-107: 374: 13.97		DREB_HUMAN (1-706): 1.28e-81: 274: 80.03
+	Hs
		998722 GAPD1_HUMAN (412-1068): 2.04e-130: 439: 13.36		EP300_HUMAN (243-695): 4.36e-30: 129: 8.61
+	Hs
		596434 RASA1_HUMAN (184-715): 9.24e-130: 428: 23.82		MAGE1_HUMAN (336-653): 7.71e-11: 67.8: 17.79