HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: GRIA3 (Q9Z2W9)
Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3)
Gene: GRIA3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27507650, 28706196, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0016020 - membrane GO:0043198 - dendritic shaft GO:0050804 - modulation of chemical synaptic transmission and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 888
+	Mm
		99914 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		GRIA2_MOUSE (3-888): 0: 857: 70.56
+	Mm
		99913 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		GRIA1_MOUSE (7-872): 0: 839: 67.86
+	Rn
		88548 D3ZCL8_RAT (16-1292): 0: 1012: 98.91		GRIA4_RAT (3-870): 0: 849: 72.73
+	Mm
		99920 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		NMDZ1_MOUSE (1-876): 0: 555: 22.18
+	Rn
		723634 SYGP1_RAT (1-1298): 0: 1033: 98.69		NMDZ1_RAT (1-876): 0: 556: 22.07
+	Mm
		723574 NF1_MOUSE (408-712): 3.83e-82: 300: 23.51		NMDZ1_MOUSE (1-876): 0: 555: 22.18