HitPredict

Interactor 1: F6VUV4 (F6VUV4)
Dehydrogenase/reductase 4 like 2
Gene: DHRS4L2

Interactor 2: DHRS4 (Q9BTZ2)
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) (Short-chain dehydrogenase/reductase family member 4)
Gene: DHRS4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004090 - carbonyl reductase (NADPH) activity GO:0005777 - peroxisome GO:0042574 - retinal metabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 278
+	Hs
		1312485 DHRS4_HUMAN (2-89): 9.78e-36: 123: 51.94		DHRS4_HUMAN (1-278): 3.09e-105: 308: 100.00
+	Ss
		1259264 DHRS4_PIG (1-89): 1.12e-34: 120: 46.15		DHRS4_PIG (1-278): 5.74e-97: 287: 82.08
+	Hs
		474671 DR4L2_HUMAN (1-90): 9.97e-33: 114: 68.70		DR4L1_HUMAN (1-278): 7.07e-85: 257: 81.14
+	Hs
		1162732 DHRS4_HUMAN (2-89): 9.78e-36: 123: 51.94		DR4L2_HUMAN (1-211): 1.07e-72: 224: 93.37
+	Zm
		21773 A0A1D6HXF7_MAIZE (2-89): 1.78e-27: 101: 31.50		A0A1D6HXF7_MAIZE (30-278): 8.72e-64: 202: 52.21
+	Ec
		468348 FABG_ECOLI (22-87): 5.51e-10: 55.4: 22.73		FABG_ECOLI (30-274): 2.61e-79: 241: 32.25
+	Hs
		1233869 DHB8_HUMAN (1-79): 9.61e-09: 52: 27.59		CBR4_HUMAN (32-278): 7.64e-74: 227: 32.39
+	Cj
		1010837 Q0PB75_CAMJE (24-84): 1.82e-09: 53.9: 21.31		Q0PB75_CAMJE (29-273): 1.26e-72: 224: 29.68