HitPredict

Interactor 1: FCHO2 (Q0JRZ9)
F-BAR domain only protein 2
Gene: FCHO2

Interactor 2: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	27237791, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 810 Hs			1 864
+	Hs
		787902 FCHO2_HUMAN (1-810): 0: 740: 100.00		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		147194 FCHO1_HUMAN (3-810): 0: 567: 43.59		EP15R_HUMAN (1-864): 1.18e-150: 466: 100.00
+	Hs
		147146 FCHO1_HUMAN (3-810): 0: 567: 43.59		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1001577 FCHO2_HUMAN (1-810): 0: 740: 100.00		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		147162 FCHO1_HUMAN (3-810): 0: 567: 43.59		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		1309722 SGIP1_HUMAN (234-580): 7.21e-10: 64.7: 25.35		EP15R_HUMAN (1-864): 1.18e-150: 466: 100.00
+	Hs
		787963 SGIP1_HUMAN (234-580): 7.21e-10: 64.7: 25.35		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1078897 FNBP1_HUMAN (11-593): 9.49e-86: 286: 15.91		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Mm
		788006 SGIP1_MOUSE (234-579): 5.18e-09: 62: 25.14		EPS15_MOUSE (1-862): 8.21e-97: 325: 41.30
+	Hs
		1078931 PACN3_HUMAN (3-405): 1.68e-70: 239: 14.45		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Sp
		195123 SYP1_SCHPO (1-533): 1.55e-63: 230: 15.29		YHLA_SCHPO (11-348): 2.49e-29: 128: 27.64
+	Rn
		1145116 PACN2_RAT (7-405): 9.58e-71: 242: 14.44		EHD1_RAT (12-102): 9.73e-24: 108: 29.67
+	Hs
		1315998 PACN1_HUMAN (1-405): 9.99e-82: 270: 16.47		EHD3_HUMAN (198-365): 3.43e-14: 78.1: 26.19
+	Hs
		1203306 FCSD1_HUMAN (15-595): 8.11e-64: 228: 12.60		ITSN2_HUMAN (2-531): 1.52e-24: 112: 11.86
+	Sc
		635278 SYP1_YEAST (19-536): 3.53e-58: 215: 12.43		EDE1_YEAST (9-832): 2.37e-28: 125: 10.51
+	Hs
		1331792 PACN2_HUMAN (7-405): 1.43e-71: 244: 14.72		EHD1_HUMAN (198-366): 4.94e-14: 77.8: 25.44
+	Hs
		1078901 SGIP1_HUMAN (234-580): 7.21e-10: 64.7: 25.35		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		1309721 SGIP1_HUMAN (234-580): 7.21e-10: 64.7: 25.35		ITSN2_HUMAN (2-531): 1.52e-24: 112: 11.86
+	Sc
		755622 BZZ1_YEAST (25-225): 1.61e-13: 76.4: 14.66		END3_YEAST (17-310): 4.94e-09: 61.2: 14.38