HitPredict

Interactor 1: PINK1 (Q0KHV6)
Serine/threonine-protein kinase Pink1, mitochondrial (EC 2.7.11.1) (PTEN-induced putative kinase 1)
Gene: PINK1

Interactor 2: PRKN (Q7KTX7)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31)
Gene: park

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 19048081, 26035866
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~ubiquitin
Common GO terms GO:0000266 - mitochondrial fission
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 11 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 721
Dm

1 482
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024