HitPredict

Interactor 1: ARL16 (Q0P5N6)
ADP-ribosylation factor-like protein 16
Gene: ARL16

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	35844135, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 414
+	Hs
		912881 ARF6_HUMAN (12-195): 2.34e-73: 220: 27.27		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		912884 ARF6_HUMAN (12-195): 2.34e-73: 220: 27.27		PABP4_HUMAN (98-274): 3.77e-37: 144: 19.02
+	Sc
		376624 ARF2_YEAST (1-196): 7.74e-75: 224: 25.63		PABP_YEAST (86-269): 2.74e-34: 136: 21.88
+	Sc
		376600 ARF1_YEAST (1-196): 6.11e-74: 222: 25.63		PABP_YEAST (86-269): 2.74e-34: 136: 21.88
+	Mm
		722696 RAB5C_MOUSE (1-197): 3.58e-64: 198: 16.58		TIA1_MOUSE (99-413): 1.08e-36: 139: 12.92
+	Hs
		734616 TRI23_HUMAN (29-189): 1.06e-13: 70.5: 31.10		TADBP_HUMAN (1-414): 4.24e-84: 264: 100.00
+	Hs
		574674 ARF4_HUMAN (1-196): 1.85e-72: 218: 26.63		HNRPD_HUMAN (81-238): 5.59e-21: 95.1: 35.93
+	Dm
		432488 ARF1_DROME (1-197): 8.87e-76: 227: 25.50		ROA1_DROME (179-271): 1.97e-16: 82.1: 24.24