HitPredict

Interactor 1: Q0P6M6 (Q0P6M6)
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (UDP-N-acetylglucosamine acyltransferase) (EC 2.3.1.129)
Gene: lpxA

Interactor 2: Q0P6M6 (Q0P6M6)
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (UDP-N-acetylglucosamine acyltransferase) (EC 2.3.1.129)
Gene: lpxA

Species: Escherichia coli

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17698807
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Acetyltransf_11~Acetyltransf_11, Hexapep~Hexapep
Common GO terms	GO:0005737 - cytoplasm GO:0008780 - acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity GO:0009245 - lipid A biosynthetic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 262 Ec			1 262
+	Cj
		1351221 LPXA_CAMJE (7-260): 3.76e-72: 223: 36.86		LPXA_CAMJE (7-260): 3.76e-72: 223: 36.86
+	Ec
		459796 LPXA_ECOLI (1-262): 6.13e-89: 266: 99.62		LPXD_ECOLI (2-197): 3.66e-43: 151: 26.47
+	Cj
		1350973 LPXA_CAMJE (7-260): 3.76e-72: 223: 36.86		LPXD_CAMJE (2-211): 9.02e-47: 160: 20.46
+	Ec
		599878 LPXD_ECOLI (2-197): 3.66e-43: 151: 26.47		LPXD_ECOLI (2-197): 3.66e-43: 151: 26.47
+	Ec
		467047 GLMU_ECOLI (3-204): 2.38e-34: 130: 14.78		GLMU_ECOLI (3-204): 2.38e-34: 130: 14.78
+	At
		1107290 SAT3_ARATH (35-211): 3.14e-33: 126: 19.80		SAT3_ARATH (35-211): 3.14e-33: 126: 19.80
+	Cj
		1350978 LPXD_CAMJE (2-211): 9.02e-47: 160: 20.46		GLMU_CAMJE (25-188): 2.79e-20: 91: 16.67
+	At
		1114902 SAT5_ARATH (48-211): 4.3e-32: 121: 17.94		SAT5_ARATH (48-211): 4.3e-32: 121: 17.94
+	At
		1115042 SAT1_ARATH (59-196): 6.07e-32: 121: 21.19		SAT1_ARATH (59-196): 6.07e-32: 121: 21.19
+	At
		1319960 GCA1_ARATH (5-220): 6.16e-30: 114: 15.98		GCA2_ARATH (5-235): 3.34e-29: 113: 14.53
+	At
		1319954 GCA2_ARATH (5-235): 3.34e-29: 113: 14.53		GCA2_ARATH (5-235): 3.34e-29: 113: 14.53
+	Hs
		1294505 GMPPB_HUMAN (7-109): 3.22e-24: 101: 16.67		GMPPA_HUMAN (5-142): 9.04e-24: 100: 15.22
+	Sp
		251586 MPG1_SCHPO (1-109): 5.37e-24: 100: 17.43		MPG1_SCHPO (1-109): 5.37e-24: 100: 17.43
+	Sp
		223845 MPG1_SCHPO (1-109): 5.37e-24: 100: 17.43		YBB2_SCHPO (3-129): 2.6e-22: 96.7: 18.94
+	At
		186857 GMPP1_ARATH (3-110): 4.16e-24: 100: 20.35		Q9C9P3_ARATH (11-107): 5.85e-13: 69.7: 16.36
+	At
		186856 GMPP1_ARATH (3-110): 4.16e-24: 100: 20.35		Q8W4J5_ARATH (4-103): 2.38e-12: 68.2: 13.76
+	At
		96218 GMPP1_ARATH (3-110): 4.16e-24: 100: 20.35		F4IFA4_ARATH (4-103): 2.38e-12: 68.2: 13.76