Interactor 1: MACA (P75830)
Macrolide export protein MacA
Gene: MACA

Interactor 2: MACB (P75831)
Macrolide export ATP-binding/permease protein MacB (EC 7.6.2.-)
Gene: MACB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 18955484
Identification Methods cross-linking study, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HlyD_D23~MacB_PCD
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0042893 - polymyxin transport
GO:0042897 - polymyxin transmembrane transporter activity
GO:0046677 - response to antibiotic
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 371
Ec

1 648
+ Tp
+ Tp
+ Cj
+ Nv

Service provided by Combinatics, Japan

Last updated: 11Aug2025