HitPredict

Interactor 1: BL1S1 (P78537)
Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein RT14) (Protein acetyltransferase BLOC1S1) (EC 2.3.1.-)
Gene: BLOC1S1

Interactor 2: BL1S2 (Q6QNY1)
Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC-1 subunit 2) (Centrosome-associated protein)
Gene: BLOC1S2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.679

The method score is based on:

Property	Details
Experiments	15102850, 33961781, 40437099
Identification Methods	affinity chromatography technology, two hybrid, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008089 - anterograde axonal transport GO:0016197 - endosomal transport GO:0031083 - BLOC-1 complex GO:0031175 - neuron projection development and 10 others more... GO:0032418 - lysosome localization GO:0032438 - melanosome organization GO:0048490 - anterograde synaptic vesicle transport GO:0051036 - regulation of endosome size GO:0060155 - platelet dense granule organization GO:0062196 - regulation of lysosome size GO:0072384 - organelle transport along microtubule GO:0098574 - cytoplasmic side of lysosomal membrane GO:0099078 - BORC complex GO:1904115 - axon cytoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	153
Hs

1	142

Service provided by Combinatics, Japan

Last updated: 11Aug2025