HitPredict

Interactor 1: FIT (Q0V7X4)
Transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (Basic helix-loop-helix protein 29) (AtbHLH29) (bHLH 29) (FER-LIKE REGULATOR OF IRON UPTAKE) (Transcription factor EN 43) (Transcription factor Fe-DEFICIENCY INDUCED TRANSCRIPTION FACTOR 1) (bHLH transcription factor bHLH029)
Gene: FIT

Interactor 2: ORG3 (Q9M1K0)
Transcription factor ORG3 (Basic helix-loop-helix protein 39) (AtbHLH39) (bHLH 39) (OBP3-responsive gene 3) (Transcription factor EN 9) (bHLH transcription factor bHLH039)
Gene: ORG3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	28650476, 18268542
Identification Methods	two hybrid, validated two hybrid, Cr-two hybrid, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0006355 - regulation of DNA-templated transcription GO:0046983 - protein dimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 318 At			1 258
+	At
		1012123 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		ORG2_ARATH (1-257): 6.52e-95: 280: 78.60
+	At
		1012129 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH100_ARATH (1-257): 1.73e-70: 218: 57.14
+	At
		1012115 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH120_ARATH (53-247): 4.99e-46: 154: 23.08
+	At
		1012126 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH126_ARATH (65-247): 8.77e-45: 151: 21.62
+	At
		1012116 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH036_ARATH (76-249): 2.67e-44: 149: 26.71
+	At
		1012119 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH125_ARATH (15-249): 4.72e-41: 143: 24.14
+	At
		1012127 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH025_ARATH (49-237): 1.45e-35: 131: 18.69
+	At
		1012117 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH101_ARATH (67-248): 1.14e-35: 128: 45.41
+	At
		97739 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH162_ARATH (72-233): 1.4e-35: 127: 21.30
+	At
		1012108 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH018_ARATH (7-238): 9.17e-28: 109: 13.88
+	At
		222008 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC2_ARATH (34-229): 2.79e-47: 167: 18.63
+	At
		1107239 MYC3_ARATH (20-304): 1.65e-47: 170: 18.34		MYC2_ARATH (34-229): 2.79e-47: 167: 18.63
+	At
		1107218 MYC2_ARATH (7-304): 9.43e-47: 168: 17.69		MYC2_ARATH (34-229): 2.79e-47: 167: 18.63
+	At
		1012110 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH071_ARATH (70-174): 1.97e-16: 79.1: 21.70
+	At
		222019 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC3_ARATH (40-229): 1.65e-44: 159: 17.56
+	At
		1323537 MYC3_ARATH (20-304): 1.65e-47: 170: 18.34		MYC3_ARATH (40-229): 1.65e-44: 159: 17.56
+	At
		222004 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC4_ARATH (18-231): 1.08e-41: 151: 18.62
+	At
		187671 MYC2_ARATH (7-304): 9.43e-47: 168: 17.69		BH014_ARATH (19-217): 6.39e-31: 120: 16.82