HitPredict

Interactor 1: FIT (Q0V7X4)
Transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (Basic helix-loop-helix protein 29) (AtbHLH29) (bHLH 29) (FER-LIKE REGULATOR OF IRON UPTAKE) (Transcription factor EN 43) (Transcription factor Fe-DEFICIENCY INDUCED TRANSCRIPTION FACTOR 1) (bHLH transcription factor bHLH029)
Gene: FIT

Interactor 2: ORG2 (Q9M1K1)
Transcription factor ORG2 (Basic helix-loop-helix protein 38) (AtbHLH38) (bHLH 38) (OBP3-responsive gene 2) (Transcription factor EN 8) (bHLH transcription factor bHLH038)
Gene: ORG2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28650476, 18268542
Identification Methods	two hybrid, validated two hybrid, Cr-two hybrid, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0006355 - regulation of DNA-templated transcription GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 318 At			1 253
+	At
		1012122 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		ORG3_ARATH (1-252): 1.56e-89: 267: 78.60
+	At
		1012129 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH100_ARATH (1-253): 4.86e-70: 217: 54.90
+	At
		1012115 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH120_ARATH (46-245): 9.3e-48: 158: 21.50
+	At
		1012126 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH126_ARATH (64-243): 2.99e-43: 147: 21.43
+	At
		1012116 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH036_ARATH (71-244): 7.64e-41: 139: 26.71
+	At
		1012127 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH025_ARATH (24-232): 1.41e-38: 138: 18.02
+	At
		1012119 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH125_ARATH (5-244): 5.25e-38: 135: 21.07
+	At
		1012117 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH101_ARATH (62-245): 3.92e-34: 124: 45.46
+	At
		97739 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH162_ARATH (67-228): 9.39e-35: 124: 21.30
+	At
		1012108 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH018_ARATH (29-233): 1.48e-31: 119: 17.05
+	At
		95719 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH167_ARATH (59-245): 1.67e-32: 118: 18.52
+	At
		1012128 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH168_ARATH (60-243): 1.3e-28: 108: 17.20
+	At
		1012110 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		BH071_ARATH (65-247): 1.83e-19: 87.6: 16.07
+	At
		222019 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC3_ARATH (31-224): 7.01e-45: 160: 17.27
+	At
		1323537 MYC3_ARATH (20-304): 1.65e-47: 170: 18.34		MYC3_ARATH (31-224): 7.01e-45: 160: 17.27
+	At
		222004 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC4_ARATH (31-224): 3.68e-43: 155: 17.59
+	At
		222008 MYC4_ARATH (10-302): 2.69e-48: 172: 19.05		MYC2_ARATH (19-224): 3.18e-42: 153: 18.02
+	At
		1012107 FIT_ARATH (1-318): 9.32e-82: 252: 100.00		FIT_ARATH (45-238): 1.05e-13: 71.4: 16.43
+	At
		1107239 MYC3_ARATH (20-304): 1.65e-47: 170: 18.34		MYC2_ARATH (19-224): 3.18e-42: 153: 18.02